The invention relates to a new process for the production of a biologically active heterologous protein. The process involves the performance of biosynthesis by adjusting conditions in such a way that the process enables the accumulation of correctly folded precursor of the heterologous protein already in inclusion bodies. The invention further comprises washing and solubilising of the inclusion bodies, especially under non-denaturating conditions.
F.32 International patent
COBISS.SI-ID: 3015194Public TV emission with confrontation of views between experts from the field of molecular biology and medical genetics, and representants of private companies offering predictive genetic testing. Considering the raising amount of services offered by private and public companies, the debate focused on questions related to froniers of science and ethics.
F.30 Professional assessment of the situation
COBISS.SI-ID: 2746760Prof. R. Komel, as coordinator of BioMedPharm consortium drew attention to irregularities occuring during the procedure of the public invitation to tender for the development of centres of excellence. In the discussion taking place at the National Council the case concerning the application of CoE BioMedPharm was used as an illustration of intolerable practices in public proceedings managed by governmental offices. His warning was well accepted by the neutral public, however less welcomed by executants and those directly involved. Legal examination of the aforesaid case is still going on.
F.30 Professional assessment of the situation
COBISS.SI-ID: 27308505Head of the Centre for Functional Genomics and Bio-chips, Prof. Damjana Rozman, chaired organization of the Fith international CFGBC symposium "From arrays to understanding disease". The meeting took place at the Faculty of Medicine of the University of Ljubljana, with 120 participants from Slovenia and abroad.
B.01 Organiser of a scientific meeting
COBISS.SI-ID: 27093209The invention relates to a modifying agent comprising a water soluble polymer, wherein the water soluble polymer comprises at least one reactive selenium group, being capable of reacting with a thiol group thereby forming an -Se-S- bond. The invention also relates to a method for producing modifying agents and their use in the modification of pharmaceutically active agents, e.g. G-CSF. It concerns a pharmaceutical composition comprising the inventive conjugates.
F.32 International patent
COBISS.SI-ID: 3912474