Within the cooperation with pharmaceutical company Krka d.d. we filed a patent that describes a synthesis of Marbofloxacin, a potent antibiotic of the fluoroquinolone group. Classical synthesis of marbofloxacin requires a multi-step process which is unpractical for a large scale manufacture, since it requires high temperatures and reagents not suitable for large-scale production, resulting in low over-all yields. Our innovation reports on an alternative approach for the preparation of marbofloxacin, which uses simple reagents and shorter reaction times with water as reaction media that obviates the use of organic solvents.
F.32 International patent
COBISS.SI-ID: 23722791Quantitative determination of nearly all the components in a W/O emulsion is possible using thermogravimetry (TG) and differential scanning calorimetry (DSC). Examples of practical apllications together with evaluations are given this chapter.
F.01 Acquisition of new practical knowledge, information and skills
COBISS.SI-ID: 34710533We have participated on 17. Slovenia Science Festival with an invited lecture on the topic "Cold light from the test tube". We have shown how we can transform chemical energy into light through chemical reaction - chemiluminescence. A topic was presented in connection with biological production of light - bioluminescence and shown some practical experiments of chemiluminescence to bring some of its magical world into the audience.
F.18 Transfer of new know-how to direct users (seminars, fora, conferences)
COBISS.SI-ID: 25132839