Several studies support the use of probiotics for the treatment of minor gastrointestinal problems in infants. Positive effects on newborn colics have been evidenced after administration of Lactobacillus strains, whereas no studies have been reported regarding the use of bifidobacteria for this purpose. This work was therefore aimed at the characterization of Bifidobacterium strains capable of inhibiting the growth of pathogens typical of the infant gastrointestinal tract and of coliforms isolated from colic newborns. Among the 46 Bifidobacterium strains considered, 16 showed high antimicrobial activity against potential pathogens; these strains were furthercharacterized from a taxonomic point of view, for the presence and transferability of antibiotic resistances, for citotoxic effects and adhesion to nontumorigenic gut epithelium cell lines. Moreover, their ability to stimulate gut health by increasing the metabolic activity and the immune response of epithelial cells was also studied. The examination of all these features allowed to identify three Bifidobacterium breve strains and a Bifidobacterium longum subsp. longum strain as potential probiotics for the treatments of enteric disorders in newborns such as infantile colics. A validation clinical trial involving the selected strains is being planned.
COBISS.SI-ID: 3337004
The Industrial Revolution and intensification of agriculture have, in some cases, led to economic activities that profoundly influenced the ecosystem to the point where environmental stability and geographic political security are jeopardized. The uncertainty about oil reserves, rising energy prices and the threat of harmful climate change effects has intensified the search for alternative farming systems that reduce negative environmental impact. This study reports the ecological impact of conventional (CON), integrated (INT), organic (ORG) and biodynamic (BD) farming systems calculated from data collected in a field trial at Maribor, Slovenia, and interpreted using the SPIonExcel tool. This tool is a member of the ecological footprint family and describes the area necessary to embed a human activity sustainably into the ecosphere. Three-year results show a markedly reduced ecological footprint of the ORG and BD systems in production of wheat (Triticum aestivum L. 'Antonius') and spelt (Triticum spelta L. 'Ebners rotkorn'), mainly due to theabsence of external production factors. When yields were also considered, the ORG and BD systems again had a reduced overall footprint per product unit and increased ecological efficiency of production. Thus, ORG and BD farming systems present viable alternatives for reducing the impact of agriculture on environmental degradation and climate change. Nevertheless, room for improvement exists in the area of machinery use in all systems studied and yield improvement in the ORG farming system.
COBISS.SI-ID: 3184428