Copper(II) complexes with the non-steroidal anti-inflammatory drugs naproxen and diclofenac have been synthesized and characterized in the presence of nitrogen donor heterocyclic ligands. The crystal structures of (2,2′-bipyridine)bis(naproxenato)copper(II), (1,10-phenanthroline)bis(naproxenato)copper(II) and bis(pyridine)bis(diclofenac)copper(II) have been determined by X-ray crystallography. Competitive study with ethidium bromide, the cyclic voltammograms and UV study have shown that the complexes bind strongly to CT DNA and to serum albumin protein.
F.02 Acquisition of new scientific knowledge
COBISS.SI-ID: 34869253Round table discussion within the National conference about communication in chemistry "Chemistry between perception and reality: role of scientists, industry, media and education", 24 May 2011, Ljubljana.
F.30 Professional assessment of the situation
COBISS.SI-ID: 15118102Chemical experiments were performed as a final lecture at the Slovenina conference of the teachers for natural sciences, Laško, 26 Aug 2011.
B.04 Guest lecture
COBISS.SI-ID: 35472901