E. coli strains instigating sepsis in immuno-compromised patients harbor fewer virulence factors than strains from nonimmuno-compromised patients. Combinations of colicins employing different receptors, translocation systems and mechanisms of activity are effective antimicrobial agents.
D.09 Tutoring for postgraduate students
COBISS.SI-ID: 739959The discovery of restriction endonucleases represented a milestone in molecular biology and biotechnology.
B.06 Other
COBISS.SI-ID: 27918297Escherichia coli strains isolated from feces of healthy individuals were characterized. Analysis with the polymerase chain reaction revealed that even though the investigated strains were isolated from healthy individuals they harbored numerous virulence factors. Results indicate that commensal E. coli strains are a potential source of extraintestinal infections.
D.10 Educational activities
COBISS.SI-ID: 3782264Genes of the SOS system, responsible for DNA repair as well as for the evolution of antibiotic resistance, exhibit heterogenous expression within populations of genetically identical bacterial cells (same strain) as well as within the framework of genetically different E. coli strains. Due to differences in gene expression we can expect differences in the capability of individual strains to adapt to environmental stress.
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COBISS.SI-ID: 3766136Protein OxyR affects expression of the gene encoding colicin K, directly or indirectly by removal of dangerous oxygen substances and via the appearance of DNA damage. Protein YdjM affects cell morphology and localization of the chromosome of E. coli during the SOS response.
D.10 Educational activities
COBISS.SI-ID: 3782008