In this work we report the preliminary crystallographic analysis of the extracellular portion of human epithelial cell adhesion molecule, EpCAM. This glycoprotein helps to regulate an array of developmental processes including cell migration, cell proliferation and differentiation, and has emerged as a target for anticancer therapies. Structural studies of this molecule are of great interest to the wider academic community. We determined the spacegroup, unit cell dimensions, and contents of the asymmetric unit, are an excellent introduction for solving the 3D structure of the protein.
COBISS.SI-ID: 35560453