The information about the structure of trans-membrane segments of proteins of known 3D structure is exploited to predict the trans-membrane domains of structurally unresolved target protein. With the help of known structures the trans-membrane domains are encoded and a model for prediction of trans-membrane segments is built. Four transmembrane alpha helices were predicted in bilitranslocase. This result is partially confirmed with experimental studies using particular antibodies corresponding to parts of amino acid sequences of bilitranslocase.
B.04 Guest lecture
COBISS.SI-ID: 4344602Amrita Roy Choudhury was awarded for the best poster at CMTPI (‘Computational Methods in Toxicology and Pharmacology integrating Internet Resources’), in Istanbul 4. -8. July 2009. The encoding of protein sequences and building of model for classification of transmembrane segments of proteins.
E.02 International awards
COBISS.SI-ID: 4193562