We analyzed over forty Saccharomycetaceae yeasts, covering over 200 million years of the evolutionary history, for their carbon metabolism. The experiments were done under strictly controlled and uniform conditions, which has not been done before. We show that the origin of Crabtree effect in Saccharomycetaceae predates the whole genome duplication and became a settled metabolic trait after the split of the S. cerevisiae and Kluyveromyces lineages, and coincided with the origin of modern fruit bearing plants. Our results suggest that ethanol fermentation evolved progressively, involving several successive molecular events that have gradually remodeled the yeast carbon metabolism.
COBISS.SI-ID: 2837243
J. Piškur and C. Compagno are editors a new book entitled "Molecular mechanisms in yeast carbon metabolism". This book covers insights into the network of genes and enzymes and molecular mechanisms balancing the metabolism of carbon compounds in the yeast cell. This book provides a dozen of most comprehensive reviews on the recent developments and achievements in the field of yeast carbon metabolism, from academic studies on gene expression to biotechnology relevant topics. Book is written by the leading scientists in the field, thus providing a first quality of the up-to-date status. J. Piškur and S. Dashko are co-authors of the chapter in this book entitled "Introduction to carbon metabolism in yeast".