The recognition of specific DNA sequences by proteins and the coupling to signaling events are fundamental occurrences that lie at the root of many cellular processes. Therefore, the study of the interaction processes between proteins and DNA is of crucial importance not only for our basic understanding of molecular function, but also for a rational approach to drug design. Here, we describe our current capabilities for studying protein–DNA interactions using NMR spectroscopy, identify the challenges and limitations in the presently available NMR methodology, and address several additional techniques that could be complimentary to the NMR results.
B.06 Other
COBISS.SI-ID: 25458215In this invited lecture our recent results of the nature of several allosteric states of the lactose represor protein, were presented.
B.04 Guest lecture
COBISS.SI-ID: 25869095In this invited lecture the description Synaptotagmin 1 as a novel binding protein for ammodytoxin was presented.
B.04 Guest lecture
COBISS.SI-ID: 25902119