Z4-4063 — Final report
1.
Autologous cell therapies for bone tissue regeneration

Mirjam Frohlich is a leading author of a chapter, entitled: ‘Autologous cell therapies for bone tissue regeneration’, in which the approaches, procedures, and clinical use of cell products for bone tissue regeneration are presented. The importance of vascularization of tissue implants is emhasized, as well as the potential of endothelial cells derived from adipose tissue for vascularization purposes.

COBISS.SI-ID: 29696217
2.
Using Cells and Biomaterials for Regeneration of Diseased and Damaged Tissues

In the Regional Biophysics Conference 2012, she had an invited lecture ‘Using Cells and Biomaterials for Regeneration of Diseased and Damaged Tissues’, in which she presented the potential of the use of adipose-derived stem cells for the purposes of regenerative medicine and in vitro testing systems for drugs and biomaterials.

COBISS.SI-ID: 27526439
3.
The plant-derived decapeptide OSIP108 inhibits Candida albicans biofilm formation without affecting cell viability

Mirjam Fröhlich is a co-author of a scientific paper ‘The plant-derived decapeptide OSIP108 inhibits Candida albicans biofilm formation without affecting cell viability’, where she employed monolayer endothelial cultures as well as tube formation test (both methods represent fundamental approaches to study endothelial function in the project) to assess the influence of the tested molecule on proliferation and tube forming potential of endothelial cells.

COBISS.SI-ID: 27520295
4.
Identification and characterization of an anti-pseudomonal dichlorocarbazol derivative displaying anti-biofilm activity

Mirjam Fröhlich is a co-author of a scientific paper ‘Identification and characterization of an anti-pseudomonal dichlorocarbazol derivative displaying anti-biofilm activity’, where she employed tube formation test (a method representing a fundamental approach to study endothelial function in the project) to assess the influence of the tested molecule on tube forming potential of endothelial cells.

COBISS.SI-ID: 28601639
5.
Effects of lentivirus transduction with Tomato Red protein on differentiation potential of human adipose derived stem cells

Mirjam Fröhlich is a first co-author of the paper ‘Effects of lentivirus transduction with Tomato Red protein on differentiation potential of human adipose derived stem cells’ Fröhlich M, Choi JH, Vunjak-Novakovic G, Kaplan D, in which she studied the effect of lentiviral transduction on ASC phenotype. Transduction enhanced the expression of osteogenic markers, but had no effect on adipogenic differentiation.