In this study, we developed the process to design carboxymethyl cellulose nanofibre mats with embedded particles of nano-hydroxyapatite, by using Elmarco pilot-scale electrospinning device Nanospider. In first stage of research, we varied the properties of the spinning solution, such as viscosity, conductivity and surface tension, the electrospinning process parameters (electrical voltage, distance between electrodes) and environmental parameters (relative humidity). Based on the analysis of the electrospun samples by scanning electron microscopy (SEM), we determined the optimal recipe for the spinning solution and the optimal conditions of the electrospinning process. In second stage, different concentrations of synthesized nano- hydroxyapatite particles (nHAp), were added to the optimum spinning solution of CMC / PEO. Based on SEM analysis of synthesized nano-hydroxyapatite particles, and results of dynamic light scattering (DLS), we have shown that the particles have a wide size distribution. We also carried out a thermogravimetric analysis (TGA) of the nanocomposite electrospun fibers, and found that the percentage of the inorganic residue, after heating, increases proportionally with increasing concentration of added particles of nano-hydroxyapatite, which confirmed the presence of particles in the fibers.
B.03 Paper at an international scientific conference
COBISS.SI-ID: 18085398In present study, a highly porous material with incorporated olive leaves extract was formed, by using electrospinning, an interesting and effective technique for production of submicron fibers and non-woven mats with outstanding properties. By using a nozzle-less electrospinning apparatus, we were able to produce unique polysaccharide nanofibrous mats with incorporated olive leaves extract, which can find application in medical field, as wound dressings, as well as in food industry. Obtained electrospun nanofibers were analyzed using HPLC method in order to prove the presence of active compounds from olive extract in the fibers. Results of HPLC analysis show mainly the presence of oleuropein compound and in smaller amount the presence of hydroxytyrosol, as well as other active fenolic compounds present in the extract, responsible for antioxidant and antimicrobial activity of developed material.
B.03 Paper at an international scientific conference
COBISS.SI-ID: 17950230The present invention relates to a carrier of silica (QCM - Quartz Crystal microbalance) crystal, which can easily be mounted or removed from electrospinning device. Essential invention of designed bracket is that it allows in-situ formation of nanofibres formed on a quartz crystal, used for further analysis on quartz microbalance (evaluation of weight and thickness of electrpspun nanofibrous mat, the adsorptive properties of nanofibres). The holder is designed so that it does not affect the operation of electrospinning device, nor the characteristics of quartz crystal and formation of electrospun fibers. With the use of invented holder we can electrospun nanofibers, on the active measuring surface of the quartz crystal, from a variety of synthetic and natural polymers with or without additives.
F.33 Slovenian patent
COBISS.SI-ID: 17802262