J4-6810 — Annual report 2014
1.
Update on C. difficile epidemiology and pathogenesis

The invited lecture at the Congres of Slovenian Society for Microbiology has given the overview on recent advances in C. difficile epidemiology, zoonotic potential and pathogenesis.

B.04 Guest lecture

COBISS.SI-ID: 3209807
2.
Molecular characterisation of clone ST398 LA-MRSA human isolates

CA- MRSA strains isolated in year 2010 that was susceptible to at least two of the following four antibiotics: ciprofloxacin, erythromycin, clindamycin or gentamicin were investigated. Altogether we collected 151 MRSA isolates of which 15 (9.9%) belonged to a spa type known to be associated with the clone ST398 respectively. Among them 12 isolates belonged to spa type t011, 2 isolates to t034 and 1 isolate to t108. We found the staphylococcal cassette chromosome - SCCmec type IV or V, and regulatory genes - agr type I. None of the isolates were positive for Panton - Valentine leukocidin (PVL), the toxic shock syndrome toxin (tst) and leukocidin LukM. All MRSA isolates were resistant to tetracycline and penicillin. Some of them were also resistant to erythromycin and clindamycin. Most of the LA-MRSA ST398 were isolated from screening specimens of patients from Murska Sobota and Maribor, which are the most important agricultural regions with intensive livestock breeding.

B.03 Paper at an international scientific conference

COBISS.SI-ID: 31704281
3.
Comparative genomics of C. difficile

Short selected oral presentation given at the Congres of Slovenian Society for Microbiology is describing the results of genomic analysis of C. difficile ribosomal intergenic region and comparatice henomics of selected C. difficile toxinotypes.

B.06 Other

COBISS.SI-ID: 512439608