Introduction of new research area in Slovenia "Nonlinear superresolution microscopy to monitor supramolecular structure changes in real time in living systems" is based on the recent investment into new 2-photon STED microscope with mwFLIM detector (0.9 MEUR), funded by Condensed matter physics department F5 IJS, ARRS call for equipment and H2020 SmartNanoTox project. Possibility to introduce new research area appeared due to first stable commercially available STED microscope in 2015, the need for supreresolved interactions between nanomaterials and cells within H2020 SmartNanoTox project and due to possibility that LBF and F5 build new optical labs and renew existing preparation labs in 2016. At the introduction of new research area, transfer of expertise in STED microscopy has been done via establishment of permanent cooperation with prof. Eggeling's group at Oxford University. Eggeling was involved in development of original STED concept as a postdoc in a group of Nobel laureate prof. Stefan Hell. Together with Eggeling's group we organised school on advanced microscopy techniques including STED. Introduction of new research area has triggered important results very soon - in just few months we 've been able to directly follow molecular event of lipid wrapping in living lung's epithelium, a phenomenon that was explored only indirectly for year before. The paper has been submitted into high-impact journal recently. New area and new equipment has been presented also during press conference in September 2017.
D.04 Initiative to set up a new research area in Slovenia
COBISS.SI-ID: 30933031Within the frame of program P1-0060, project ARRS L7?7561 and project GOSTOP new modular development site has been setup in new optical labs to test various versions for smart ophthalmic devices. Within the research work at the end of 2017 we have unexpectedly discovered that the current FMS analysis can be modified to enable mapping of absorber molecules, which is useful in identification of vessel leakage and which is the content of the recently filled patent application. Program group P1-0060 or Laboratory of Biophysics in particular has established permanent cooperation with Optotek medical company in the field of development of diagnostic and theranostic technologies. In the field of medical laser devices we collaborate with Fotona as well as with group of R.Petkovšek on Faculty of mechanical engineering of University of Ljubljana. Program group P1-0060 has gained several industrial contracts in the last years for various demonstrator developments or other market oriented research (development of a device to identify NIR-protection of money with Radeče papir nova company; measurement of dissolution process for Krka company; measurement of food cutting on the cellular level during blending for BSH company)
F.21 Development of new health/diagnostic methods/procedures
COBISS.SI-ID: 31223079An international workshop in Bled on NMR/MRI methods for the study of materials is organized annually. The organization alternates between German (Hirschegg) and Romanian (Cluj) in Slovene (Bled) partners. This time the workshop was organized for the second time in Bled. Throughout the last year we organised several events for efficient knowledge transfer as well. In September we hosted a three-day workshop “Exploring the molecular world by advanced fluorescence microscopy approaches” to present numerous research possibilities offered by the new 2PE STED microscope, installed within LBF/F5/IJS. The lectures and practicals were performed together with our collaborators from the University of Oxford. Every year we organised the traditional “Days of Biophysics”. During short lectures, knowledge market, and interactive poster presentations we explored applications of biophysics in pharmacy. With lectures and practical demos we participated also at the international workshop “Cellular Imaging Techniques” in Turkey. Laboratory of Biophysics is coordinating the organisation of international Regional Biophysics Conference 2018 in Zreče (Slovenia), which host the regional biophysicists from Italy, Austria, Hungary, Croatia, Serbia, Slovakia and Slovenia and appears to one of the most important European biophysics events between two subsequent EBSA european conferences. Similarly we were involved in organisation of the previous RBC meetings in Trieste (2016, Italy), Smolenice (2014, Slovakia), Kladovo (2012, Serbia), Primošten (2010, Croatia).
B.01 Organiser of a scientific meeting
COBISS.SI-ID: 291636736Our group is continuously engaged in young PhD student training. In the last 10 years 14 new PhD succesfully defended their dissertations with supervision by the membes of P1-0060 together with 46 diploma thesis candidates and 25 master student candidates. We are continuously involved in teaching courses at different faculties in Slovenia. For example at Bologna I and II level: prof. dr. Janez Štrancar (FPhysical measurements (UNI-MB FNM Fizika), Advanced experimental methods in physics and biophysics (UNI-MB FNM Fizika II), Molecular biophysics (UNI-LJ FFA LBM II)), prof. dr. Igor Serša (Physics (UNI-LJ FFA LBM), Physics of anatomical imaging (UNI-LJ FMF MEF II)), doc. dr. Aleš Mohorič (Comission for Matura, Physics 1 (UNI-LJ FMF FMT), Physical praktikum I and II as well as Project work I and II (UNI-LJ FMF Fizika 1), How things works? (UNI-LJ FMF PEF), Methodical praktikum (UNI-LJ FMF)) doc. dr. Zoran Arsov (Imaging methods (UNI-LJ FFA LBM II).
D.09 Tutoring for postgraduate students
COBISS.SI-ID: 280326144Aleš Mohorič serves as an Editor of Obzornik za matematiko in fiziko (2008-) published by The Society of Mathematicians, Physicists and Astronomers of Slovenia as well as the Editor of Preseka - journal for young mathematicians , physicists, astronomers and computer enthusiasts published also by The Society of Mathematicians, Physicists and Astronomers of Slovenia. Gorazd PLaninšič was member of editorial board of Physics Education (2008) as well as editorial board of the report for the project Development of the natural sciences competences. Janez Štrancar edited the report for the Center of Excellence NAMASTE (2012).
C.05 Editorial board of a national magazine