Expression of ESR1 and PGR was quantified in mammary tissue-derived primary goat mammary epithelial cells (pgMECs) to determine the influence of donor tissue physiology (lactating and juvenile) and cell culture growth conditions (basal and lactogenic) on ESR1 and PGR expression in the derived cells. Relative mRNA levels for both receptors were the highest in cell lines derived from mammary tissue of juvenile goats. The derived primary cultures/lines in early passages are hormone-responsive and represent a useful surrogate system for mammary tissue.
COBISS.SI-ID: 3713928