The research programme develops methods of bioindication of environmental pollution and land use change in terrestrial ecosystems. These investigations are carried out at all levels of biological organisation, eg. from biochemical and physiological investigations at the cell level to study of response of whole organisms. Investigations are integrated in a broader European scale contributiong important data for studying harmul impacts of environmental pollution and land use change in global scale. Investigations of plants at natural carbone dioxide springs provide valuable data about effects of elevated corbon dioxide on natural and agricultural plants at this unique habitat, demanding relatively low costs. Results are interesting for the science what is proved by publications of data in relevant journals (published review article in journal Progress in Botany). On the field of genetics the results of investigation of glicemic index (GI) of buckwheat and spelt wheat are important (cited in American Journal of Clinical Nutrition). Results of interactions among genetic and ecological factors influencing the accumulation of rutin in tartary buchwheat are also important (published Journal of Agricultural and Food Chemistry). In the field of investigations of medical and aromatic plants the interdisciplinary approach among botany, chemistry, agronomy and medicine is important. Investigations of plant extracts and biotechnological production of plant secondary compounds are new and outstanding in the results were published in international journals. In the field of scientific information in biotechnology the research group members participate in the international information systems ( AGRIS7WAICENT, AgroWeb)