Investigations on mechanisms for maintenance and regeneration in the ageing muscle : development of guidelines , diagnostic tools and a view to therapies

Raziskovalci (1)

št.	Evidenčna št.	Ime in priimek	Razisk. področje	Vloga	Obdobje	Štev. publikacijŠtev. publikacij
1.	02132	dr. Miha Žargi	Onkologija	Vodja	2000 - 2003	392

Organizacije (1)

št.	Evidenčna št.	Razisk. organizacija	Kraj	Matična številka	Štev. publikacijŠtev. publikacij
1.	0510	Univerza v Ljubljani	Ljubljana	5085063	250

Povzetek

Diminution in muscular performance is a major cause of disablement in old age. This loss appears to be a multi component phenomenon. We will investigate whether and which factors within the muscle itself are responsible for this decline. A major goal of our network is to determine changes in the behaviour of the satellite cells during ageing (i.e. numbers, proliferate capacity in vitro and in vivo, gynogenic program, calcium homeostasis). Satellite cells are the only source for maintenance, growth and regeneration of muscle tissue. Important aspects of the contractile apparatus and capillarization will be investigated as well. Most work will be performed on human tissue in a cooperation of outstanding basic scientists and clinical partners. A diagnostic tool to predict trainability of muscle in the aged will be elaborated.

Filtri

Investigations on mechanisms for maintenance and regeneration in the ageing muscle : development of guidelines , diagnostic tools and a view to therapies

Zgodovina ogledov

Priljubljeno

Filtri

Investigations on mechanisms for maintenance and regeneration in the ageing muscle : development of guidelines , diagnostic tools and a view to therapies

Zahtevana je potrditev

Zgodovina ogledov

Priljubljeno