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Projects
Functional physiologically active plant materials with additional values for application in pharmaceutical and food industry
Research activity
| Code | Science | Field |
|---|---|---|
| B230 | Biomedical sciences | Microbiology, bacteriology, virology, mycology |
| B740 | Biomedical sciences | Pharmacological sciences, pharmacognosy, pharmacy, toxicology |
| T150 | Technological sciences | Material technology |
| T350 | Technological sciences | Chemical technology and engineering |
| T410 | Technological sciences | Pharmaceuticals and related technologies |
Keywords
Natural material, supercritical extraction, antimicrobial activity, topical and systemic application
Organisations (8) , Researchers (2)
0016 University of Belgrade, Faculty of Technology and Metallurgy
| no. | Code | Name and surname | Research area | Role | Period | No. of publicationsNo. of publications |
|---|---|---|---|---|---|---|
| 1. | 03067 | Chemical technology and engineering | Head | 2011 - 2019 | 64 |
0025 University of Belgrade, Faculty of Veterinary Medicine
0036 University of Novi Sad, Faculty of Technology
0099 University of Nis, Faculty of Medicine
| no. | Code | Name and surname | Research area | Role | Period | No. of publicationsNo. of publications |
|---|---|---|---|---|---|---|
| 1. | 11279 | Analytical chemistry | Researcher | 2011 - 2019 | 37 |
0117 University of Nis, Faculty of Sciences and Mathematics
0124 Institute of Medicinal Plants Research "Dr Josif Pancic"
0148 Economics Institute
0242 Innovation Center, Faculty of Technology and Metallurgy in Belgrade Ltd (IC)
Abstract
The aim of this project is technology development for production of functional plant materials for application in pharmaceutical and food industry on the basis of domestic raw materials as well as formulation of at least six products. Within the project 26 medical plants will be investigated from the point of the antibacterial and antimycotic (antifungal) activity of their extracts. For the chosen extracts, antioxidant, antiviral and cytotoxic activity will be tested as well. Methods of active principles isolation will be supercritical fluid extraction with carbon dioxide, extraction with organic solvents and hydrodistillation. Antibacterial activity of obtained extracts will be tested against chosen staphylococci strains, including MRSA strains, as well as against food pathogens. For antimycotic investigations, Candida Microsporum and Trichophyton strains will be used. For the antiviral investigations, a number of viruses from the families Herpesviridae (BHV-1) and Paramyxovirus (Newcastle) will be used. For the biologically most active plant extracts, possibility of their adsorption on solid carriers (biopolymers, polymers, silica based, clays, oxides, sugars, proteins, cellulose, starch) under high pressures using supercritical fluids will be investigated. On the basis of obtained results on antibacterial, antimycotic and antiviral activities, at least six products will be formulated and produced - three for topical and three for systemic application.