Projects / Programmes source: ARIS

System Approach To Stress Management

Research activity

Code Science Field Subfield
3.09.00  Medical sciences  Psychiatry   

Code Science Field
B650  Biomedical sciences  Psychiatry, clinical psychology, psychosomatics 

Code Science Field
3.02  Medical and Health Sciences  Clinical medicine 
Contextualising research in existing institutional and international research programmes and projects
Evaluation (rules)
source: COBISS
Researchers (7)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  29860  PhD Voyko Kavcic  Neurobiology  Researcher  2016 - 2019  159 
2.  12481  PhD Blanka Kores Plesničar  Psychiatry  Researcher  2016 - 2019  398 
3.  30987  PhD Nika Lalek  Microbiology and immunology  Researcher  2016 - 2018  51 
4.  12939  PhD Maja Rus Makovec  Psychiatry  Researcher  2016 - 2019  244 
5.  22235  PhD Borut Škodlar  Psychiatry  Researcher  2016 - 2019  517 
6.  05379  PhD Bojan Zalar  Medical sciences  Head  2016 - 2019  175 
7.  02703  PhD Martina Žmuc Tomori  Psychiatry  Retired researcher  2016 - 2019  547 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  1620  University Psyhiatric Hospital  Ljubljana - Polje  1191004000  3,485 
The programme shall provide conditions for systemic examination of different distress – disease conditions in a specific way; though a new idea and interaction of different data linked with health and disease. The most modern approaches and research methodology shall be used. In addition to patients, their relatives shall be included in research, providing for environment where small differences impacting integration and having a decisive impact on an event or disease shall be considered. We shall be limited to examining three groups of patients based on classification of disease as physical (carcinoma), psychosomatic (asthma, chronical obstructive bronchitis), and mental (depression). All three groups shall be examined on multilevel basis: personally, cognitively, emotionally, psycho physiologically, genetically. We shall burden them with mental stress, control distress and discontinue distress after two standard deviations from subjective average. We shall assess basic condition, after application of stress condition and homeostatic process. In appropriate time intervals small samples of blood shall be taken (up to 5 ml), which is less invasive method; the other assessment procedures are mainly non-invasive (exp. saliva samples, EMG, EDR or psycho- diagnostics). Samples of saliva are important to assess previous serious actions or abuse caused by stress, since alterations in epigenome inscriptions are visible in tissues, also in saliva. The brain and microbiome in the intestines communicate within homeostatic paths including nervous, endocrine and immunological signals. Microbiome can modify epigenomic inscriptions. Physical diseases have also mental background; on the other hand, exp. depression has impact on physical body, exp. cardiac and brain vascular diseases, high blood pressure, diabetes type 2. New research approach is necessary for understanding and professional development, change of life style and control over reactions and management as well as prevention of harmful reactions and events.
Significance for science
Systemic approach to exploration is inevitable contemporary feature representing and explaining complex phenomena. In addition to data relating to the structure of stress in various distress (mental psychosomatic, and somatic) conditions, similarities and differences, the presented research will reveal relations and relatives’ characteristics and mixes. This will be an important step for forming the hypothesis of emergence of mental and somatic disorders and diseases and the interactions between the mental and the physical. Interactive and interdisciplinary approach shall contribute to global understanding of stress impacts and enable more effective strategies for stress confrontation beyond relaxation techniques, often not possible to implement or lacking effect. Some people cannot relax using one relaxation technique; some cannot relax using any, and some can relax using any. Most can learn strategies to control themselves and the environment; organised confrontation with problems and issues. Recognition and acceptance that some problems cannot be solved can help individuals in confronting stress. An important upgrade of the research is inclusion of relatives; the research results shall extremely increase the data environment with extremely important information enabling definition of risk factors. One of the first approaches shall be integration of epigenomic and microbiomic data with the data of exposome. We shall learn about the inclination to stress response and contribute to more complex understanding of links between stress and diseases.
Significance for the country
The programme shall improve understanding of disease, stress. And stress influences on development, mix and disposition combination of an individual in interaction with environment. Understanding of processes enables planning, adaptation, understanding, and the influence of experience and prevention activities. Health and faster recovery diminish absenteeism, influence quality of life, increase satisfaction and make an impact on productivity.
Most important scientific results Annual report 2016, 2018, final report
Most important socioeconomically and culturally relevant results Annual report 2016, 2017, 2018, final report
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