Projects / Programmes
Eye diseases of adults and children
January 1, 2019
- December 31, 2027
| Code |
Science |
Field |
Subfield |
| 3.03.00 |
Medical sciences |
Neurobiology |
|
| 3.01.00 |
Medical sciences |
Microbiology and immunology |
|
| Code |
Science |
Field |
| B620 |
Biomedical sciences |
Ophtalmology |
| Code |
Science |
Field |
| 3.01 |
Medical and Health Sciences |
Basic medicine |
Eye diseases, pediatric ophthalmology, diagnostics of eye diseasesi, genotipe-phenotype characterization of eye diseases, treatment of eye diseases
Data for the last 5 years (citations for the last 10 years) on
April 18, 2024;
A3 for period
2018-2022
| Database |
Linked records |
Citations |
Pure citations |
Average pure citations |
| WoS |
478 |
7,311 |
6,657 |
13.93 |
| Scopus |
489 |
8,936 |
8,218 |
16.81 |
Researchers (25)
Organisations (2)
Abstract
Programme is diverse and is organised in sections led by the experts in respective fields. In every of the sections of the proposed programme, common characteristic is in early recognition and understanding of the mechanisms of damage and timely introduction of corrective therapy whenever available. In the next programme period, we would like to continue with the work charted in the period between 2009-2013. We would therefore like to keep the following parts of the program as follows:
1.DYSTROPHIES AND DEGENERATIONS AND INFLAMMATORY DISEASES OF RETINA AND OPTIC NERVE (leader prof.dr.M.Hawlina)
We wish to continue the work with phenotype-genotype correlations and characterisation of retinal dystrophies and inherited optic neuropathies, macular degenerations and on inflammatory eye diseases.
2.ELECTROPHYSIOLOGICAL FUNCTION OF THE RETINA AND VISUAL PATHWAY (leader: dr. M. Šuštar)
Wie wish to implement new, more sensitive electrophysiological methods to assess early changes and follow up of retinal and optic nerve function in children and adults
3.CLINICAL STUDIES OF CHILD'S VISION (leader doc.dr.Manca Tekavčič Pompe)
We wish to coninue to investigate sensory disturbances in congenital nystagmus and disturbances in visual pathway with or without associated developmental disorders of the central nervous system and investigate the development of vision in premature infants and children with brain disorders.
4.CLINICAL AND ULRASTRUCTURAL CHARACTERISTICS OF THE CORNEA AND LENS (leader prof.dr. M.Hawlina)
We wish to continue investigations of ultrastructure of anterior lens capsule and cornea and to implement treatment of corneal diseases with stem cells.
5.DIABETIC RETINOPATHY (leader prof.dr.M. Globočnik Petrovič)
We wish to continue our studies and to assess specific mRNA and phenotypic expression of gene polymorphisms in pathogenesis of DR and asses the prognostic biomarkers for its development.
6.GLAUCOMA (leader prof.dr.B.Cvenkel)
We wish to continue our studies and also to assess the possible correlation between different activities of the patients with specific visual field defects, to assess correlation with vessel density and to assess pharmacogenomical biomarkers for development of disease and efficacy of treatment.
7. LASER TREATMENT ON THE OCULAR AND PERIOCULAR TISSUES (leader as. dr. Gregor Hawlina)
We wish to continue to study the effects, continue develpment and clinical use of lasers for dacryocystorhinostomy and YAG lasers for use in anterior segment of the eye and periocular skin neoplasms.
8.TRANSLATION EXPERIMENTAL STUDIES: (leaders: dr.S.Andjelić, dr.G.Belušič, prof.dr.M. Hawlina) We wish to continue the work on mechanisms of cataractogenesis. We wish to expand the techniques of culturing corneal stem cells that are important in the treatment of corneal diseases. We also wish to develop new objective method of color vision testing.
Significance for science
All proposed sections of the programme bring new scientific information of clinical importance. Scientific findings bring possibilities of better understanding of diseases and better diagnostics and treatment. Important aspects of very early diagnosis of retinal dystrophies and degenerations, diabetic retinopathy and glaucoma, diseases of the cornea and lens as well as in pediatric neuroophthalmic diseases, in which it may be possible to prevent the loss of vision. Research on genetic causes of these diseases are important for diagnosis and prognosis and hopefully, for genetic treatment when it becomes available. Research on laser irradiation on the ocular and periocular tissues is important to optimise the medical laser from the concepts to pre clinical and clinical use. It is expected that the scientific findings obtained within this program will have direct impact on better diagnosis and treatment of ocular diseases.
Significance for the country
In Slovenia, our research programme brings new possibilities to introduce modern diagnostic and treatment methods. This is also important in obtaining new diagnostic equipment that is important for both, development of scientific methods as well as improvement of clinical applications. Results of use of new equiopment have been published in three issues of Slovenian Medical Journal, Zdravniški vestnik and the fouth one is going to be issued shortly. Introduction of new methods do have direct impact on the health of the population. Modern diagnostics and treatment offer immediate benefit to the patients whilst the genetic research brings understanding of slovenian types of mutations and although this may still be a long process, it promises to alleviate or at least slow down the progression of genetic diseases. it is also very important to have the opportunity to develop our medical research personnel as well as our dedicated technical staff.
Most important scientific results
Interim report
Most important socioeconomically and culturally relevant results
Interim report
