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Projects / Programmes source: ARIS

New Conventional and Additive Manufactured Biodegradable Fe-Mn alloy with Tailored Biodegradability

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Research activity

Code Science Field Subfield
2.04.02  Engineering sciences and technologies  Materials science and technology  Metallic materials 

Code Science Field
T450  Technological sciences  Metal technology, metallurgy, metal products 

Code Science Field
2.05  Engineering and Technology  Materials engineering 
Keywords
Biodegradable Implant, Fe-Mn Alloy, Additive Manufacturing, Stent, Porous Implant, Grain Boundary Engineering, Laser Surface Texturing
Evaluation (rules)
source: COBISS
Evaluation of bibliographic research performance indicators according to ARIS methodology
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Researchers (16)
no. Code Name and surname Research area Role Period No. of publications
1.  35645  PhD Jaka Burja  Materials science and technology  Researcher  2019 - 2022  321 
2.  25126  PhD Črtomir Donik  Materials science and technology  Researcher  2019 - 2022  316 
3.  11155  PhD Damjana Drobne  Biology  Researcher  2019 - 2022  863 
4.  21559  PhD Darja Feizpour  Materials science and technology  Researcher  2021 - 2022  174 
5.  10842  PhD Matjaž Godec  Materials science and technology  Head  2019 - 2022  883 
6.  29224  PhD Peter Gregorčič  Manufacturing technologies and systems  Researcher  2019 - 2022  263 
7.  32545  PhD Matej Hočevar  Materials science and technology  Researcher  2021 - 2022  153 
8.  18475  PhD Aleksandra Kocijan  Materials science and technology  Researcher  2019 - 2022  255 
9.  26027  PhD Andraž Kocjan  Materials science and technology  Researcher  2020  74 
10.  53121  Tjaša Kranjec  Materials science and technology  Researcher  2021  14 
11.  36464  PhD Tijan Mede  Materials science and technology  Researcher  2020 - 2022  13 
12.  28660  PhD Irena Paulin  Materials science and technology  Researcher  2019 - 2022  317 
13.  15269  PhD Bojan Podgornik  Materials science and technology  Researcher  2019 - 2022  1,130 
14.  26237  PhD Marko Sedlaček  Materials science and technology  Researcher  2019 - 2022  248 
15.  04101  PhD Božidar Šarler  Process engineering  Researcher  2019 - 2022  1,101 
16.  04254  PhD Janez Šetina  Electronic components and technologies  Researcher  2019 - 2022  251 
Organisations (3)
no. Code Research organisation City Registration number No. of publications
1.  0206  Institute of Metals and Technology  Ljubljana  5051622000  5,977 
2.  0481  University of Ljubljana, Biotechnical Faculty  Ljubljana  1626914  66,295 
3.  0782  University of Ljubljana, Faculty of Mechanical Engineering  Ljubljana  1627031  29,207 
Abstract
The proposed project will be an intensive, interdisciplinary collaboration that brings together researchers from the fields of chemistry, physics, metallurgy and mechanical engineering. As a result, we expect to see the output of important, original, basic science results, as well as results that have a strong application potential. Biodegradable metals and alloys are gaining increasing attention for implant applications, in particular for the skeletal and vascular systems. The advantages of the tailored degradation of temporary supporting devices allow healing processes for diseased tissue, while the possible disadvantages of permanent implants, like revision surgery, prolonged physical irritation, chronic inflammation, lacking adaptation to growth, or in-stent restenosis, can be overcome. The proposed project brings new aspects to the design of absorbable metallic materials for biomedical applications by introducing different approaches. It combines a conventional metallurgical approach with advanced laser techniques, such as surface laser texturing and additive manufacturing. Therefore, it opens up completely new routes for the development of new, bio-absorbing alloys that have tremendous potential to become important for a diversity of biomedical applications. In this way, the proposed research opens up the possibility for the development of completely new research directions based on an interdisciplinary approach, combining photonics, materials science and medicine. Grain-boundary engineering is an important approach to dramatically changing the corrosion properties of metallic materials. Researchers have, for a long time, made enormous efforts to improve the corrosion properties of metals, but there is lack of information about using grain-boundary engineering to enhance corrosion. Gaining knowledge in this field will open up a completely new research area and make it possible to also use this knowledge in other research fields. More and more researchers are trying to develop new implants by using additive manufacturing. However, none (or very few) are using AM to build biodegradable implants. With AM technology we have the freedom of design and can develop parts with a porous structure and the possibility to mimic the natural structure of bones and other “bio” parts. Porous structures enable us to tailor the proper mechanical properties, similar to that of bones. Porous structures also enable enhanced corrosion with an increased surface area. The implants should have a similar porosity to that of natural bones in order to transfer cells, nutrients, etc. Gaining knowledge in the interdisciplinary field of material science and medicine is crucial for implants’ development. Furthermore, we will study the influence of mixing different powders in order to tailor the corrosion and other properties of the developed material using AM technology. This approach allows us to create materials that are not possible to produce with conventional metallurgical approaches. It is expected that this knowledge will be used in other areas of material development that go far beyond the boundaries of this project.
Significance for science
The project will be an intensive, interdisciplinary collaboration that brings together researchers from the fields of chemistry, physics, metallurgy and mechanical engineering. As a result, we expect to see the output of important, original, basic science results, as well as results that have a strong application potential. Biodegradable alloys are gaining attention for implant applications, in particular for the skeletal and vascular systems. The advantages of the tailored degradation of temporary supporting devices allow healing processes for diseased tissue, while the possible disadvantages of permanent implants, like revision surgery, prolonged physical irritation, chronic inflammation, lacking adaptation to growth, or in-stent restenosis, can be overcome. The proposed project brings new aspects to the design of absorbable metallic materials for biomedical applications by introducing different approaches. It combines a conventional metallurgical approach with advanced laser techniques, such as surface laser texturing and AM. Therefore, it opens up new routes for the development of new, bio-absorbing alloys that have tremendous potential to become important for a diversity of biomedical applications. In this way, the proposed research opens up the possibility for the development of new research directions based on an interdisciplinary approach, combining photonics, materials science and medicine. Grain-boundary engineering is an important approach to dramatically changing the corrosion properties of metallic materials. Researchers have, for a long time, made enormous efforts to improve the corrosion of metals, but there is lack of information about using grain-boundary engineering to enhance corrosion. Gaining knowledge in this field will open up a completely new research area and make it possible to also use this knowledge in other research fields. More and more researchers are trying to develop new implants by using AM. However, only few are using AM to build biodegradable implants. With AM technology we have the freedom of design and can develop parts with a porous structure and the possibility to mimic the natural structure of bones. Porous structures enable us to tailor the proper mechanical properties, similar to that of bones. Porous structures also enable enhanced corrosion with an increased surface area. The implants should have a similar porosity to that of natural bones in order to transfer cells, nutrients, etc. Gaining knowledge in the interdisciplinary field of material science and medicine is crucial for implants’ development. Furthermore, we will study the influence of mixing different powders in order to tailor the corrosion and other properties of the developed material using AM technology. This approach allows us to create materials that are not possible to produce with conventional metallurgical approaches. It is expected that this knowledge will be used in research areas that go far beyond the boundaries of this project.
Significance for the country
The project will be an intensive, interdisciplinary collaboration that brings together researchers from the fields of chemistry, physics, metallurgy and mechanical engineering. As a result, we expect to see the output of important, original, basic science results, as well as results that have a strong application potential. Biodegradable alloys are gaining attention for implant applications, in particular for the skeletal and vascular systems. The advantages of the tailored degradation of temporary supporting devices allow healing processes for diseased tissue, while the possible disadvantages of permanent implants, like revision surgery, prolonged physical irritation, chronic inflammation, lacking adaptation to growth, or in-stent restenosis, can be overcome. The proposed project brings new aspects to the design of absorbable metallic materials for biomedical applications by introducing different approaches. It combines a conventional metallurgical approach with advanced laser techniques, such as surface laser texturing and AM. Therefore, it opens up new routes for the development of new, bio-absorbing alloys that have tremendous potential to become important for a diversity of biomedical applications. In this way, the proposed research opens up the possibility for the development of new research directions based on an interdisciplinary approach, combining photonics, materials science and medicine. Grain-boundary engineering is an important approach to dramatically changing the corrosion properties of metallic materials. Researchers have, for a long time, made enormous efforts to improve the corrosion of metals, but there is lack of information about using grain-boundary engineering to enhance corrosion. Gaining knowledge in this field will open up a completely new research area and make it possible to also use this knowledge in other research fields. More and more researchers are trying to develop new implants by using AM. However, only few are using AM to build biodegradable implants. With AM technology we have the freedom of design and can develop parts with a porous structure and the possibility to mimic the natural structure of bones. Porous structures enable us to tailor the proper mechanical properties, similar to that of bones. Porous structures also enable enhanced corrosion with an increased surface area. The implants should have a similar porosity to that of natural bones in order to transfer cells, nutrients, etc. Gaining knowledge in the interdisciplinary field of material science and medicine is crucial for implants’ development. Furthermore, we will study the influence of mixing different powders in order to tailor the corrosion and other properties of the developed material using AM technology. This approach allows us to create materials that are not possible to produce with conventional metallurgical approaches. It is expected that this knowledge will be used in research areas that go far beyond the boundaries of this project.
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