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Projects / Programmes source: ARIS

Mozgansko zilna reaktivnost in delovanje avtonomnega zivcevja pri cloveku v normalnih in patoloskih razmerah (Slovene)

Research activity

Code Science Field Subfield
3.03.00  Medical sciences  Neurobiology   
Keywords
(a) transcranial doppler sonography, migraine, diabetes mellitus, autonomic neurocardiology (b) acute ishcemic stroke, autonomic nervous system, neuricardiology
Evaluation (rules)
source: COBISS
Researchers (7)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  18480  Valentin Beznik    Researcher  2000 - 2002 
2.  10693  PhD Jan Kobal  Neurobiology  Researcher  2000 - 2002  144 
3.  10679  MSc Bernard Meglič  Neurobiology  Researcher  2000 - 2002  135 
4.  05347  PhD Tomaž Pogačnik  Neurobiology  Head  2000 - 2002  165 
5.  11647  PhD Marjan Zaletel  Neurobiology  Researcher  2000 - 2002  724 
6.  17693  Anka Žekš    Researcher  2000 - 2002 
7.  05352  PhD Bojana Žvan  Neurobiology  Researcher  2000 - 2002  801 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0312  University Medical Centre Ljubljana  Ljubljana  5057272000  77,742 
Abstract
a) With cerebrovascular reactivity we can, by using various physological stimuli, assess the functioning of different parts of regulation of cerebrovascular blood flow. Using the visual stimulus we can assess the metabolic regulation or function of neurovascular correlation. Using the head-up tilt test we could control the symphatetic function in big cerebral arteries; by inhalation of 5% CO2 gas mixture and intravenous injection of L-arginine we could assess the NO system. By determining cerebrovascular reactivity (CVR) we could estimate the function of nerovascular relations in patients with migraine and cerebral autoregulation in diabetic patients with autonomic neuropathy and find the possible dysfunction of NO system. b) The role of autonomic nervous system in younger patients who suffered an ischemic stroke is not completly clarified yet. The studies on that field have been scare . Due to propositions, variability in autonomic nervous system activity may largely contribute to development of brain infarction, most probably due to its influence on brain arteries reactivity. The autonomic nervous system reactivity in younger patients is more pronounced than in older ones. We intend to clarify the role of autonomic nervous system in young stroke patients by using neurocardiologic tests, while localisation and/or extent of infarction will be evalueted by MRI.
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