Projects / Programmes source: ARIS

Organska kemija (Slovene)

Research activity

Code Science Field Subfield
1.04.00  Natural sciences and mathematics  Chemistry   

Code Science Field
P390  Natural sciences and mathematics  Organic chemistry 
Evaluation (rules)
source: COBISS
Researchers (12)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  21343  PhD Sergeja Bombek  Pharmacy  Researcher  2001 - 2003  31 
2.  21173  PhD Marjan Ješelnik  Chemistry  Researcher  2001 - 2003  30 
3.  17138  Zdenka Kadunc    Researcher  2001 - 2003 
4.  03904  PhD Marijan Kočevar  Chemistry  Researcher  2001 - 2003  573 
5.  13822  PhD Janez Košmrlj  Chemistry  Researcher  2001 - 2003  506 
6.  20063  PhD Krištof Kranjc  Chemistry  Researcher  2001 - 2003  256 
7.  05044  PhD Andrej Petrič  Chemistry  Researcher  2001 - 2003  207 
8.  02310  PhD Slovenko Polanc  Chemistry  Head  2001 - 2003  549 
9.  19527  Irena Povalej    Researcher  2001 - 2003 
10.  19405  PhD Franc Požgan  Chemistry  Researcher  2001 - 2003  373 
11.  18423  PhD Bogdan Štefane  Chemistry  Researcher  2001 - 2003  394 
12.  02314  PhD Bojan Verček  Chemistry  Researcher  2001 - 2003  149 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0103  University of Ljubljana, Faculty of Chemistry and Chemical Technology  Ljubljana  1626990  22,689 
The studies involve one-step tandem cyclizations leading to '5+5' and '5+6' bi-cyc-lic heterocycles. The applications of ?- and ?- amino acids for the preparation of imidazo/1,2-a/pyrimidinyl sugars are planned. Further activities include trans-for-mat-ions of ?-amino acids towards imidazo/1,2-a/pyridines, imidazo/1,2-a/quino-lines and pyrido/1,2-a/pyrazines. We also investigate new approaches to spiro-oxazo-line systems that employ 1,2-diamino- aromatic or heteroaromatic compounds and 2-benzoyl-amino-3-chloropropenoic acid. Another studies deal with the transformation of pyran-2-on building block into didehydroamino acid derivatives. Cycloadditions, sub-stitutions and other reactions under high pressure (10?15 kbar) are also a part of our endeavours. Furthermore, applications of diazenecarboxamides for the selective oxidations of thiols to disulfides and selenols to diselenides are studied. The same diazene-carboxa-mides are also subjected to cyclic voltammetry to get more information concerning their cathodic potentials. Another aspect of diazenecarboxamides involves their abilities as the reagents for aromatic electrophilic aminations, which results in regioselective processes regarding both partners. Depending on the reactivity of an aromatic substrate one can expect either inter- or intramolecular reaction. New compounds which can serve as fluorescent probes are also studied. The research is directed to new derivatives that can easily be employed for the introduction of radioactive fluorine atom (18F). The 18F labelled species are applied in collaboration with our colleagues from UCLA for the in vitro and in vivo studies of the changes of the central nerve system connected with the Alzheimer disease. Furthermore, new deriva--tives containing tropane skeleton are prepared in order to serve in Positron Emission Tomo-graphy (PET) to follow the changes in dopamine system (the Parkinson disease, abuse of drugs, etc.).
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