Projects / Programmes
January 1, 1999
- December 31, 2003
| Code |
Science |
Field |
Subfield |
| 2.02.00 |
Engineering sciences and technologies |
Chemical engineering |
|
| Code |
Science |
Field |
| T350 |
Technological sciences |
Chemical technology and engineering |
| T490 |
Technological sciences |
Biotechnology |
Researchers (8)
Organisations (1)
Abstract
I. Extraction processes – Extraction solid-SCF in liquid SCF:
We have determined a new type of S-L-G phase transition. Our research programme was oriented towards:
1. The determination of high-pressure equilibrium data of solids and liquids in liquid and supercritical gasses with a static-analytic and/or dynamic method. With regard to P-T-x projections, we have determined areas of total mixing between the compressed media and solute;
2. The evaluation of thermodynamic correlations of solubility data, which are based on the density correlation or equation of state in binary and ternary systems;
3. The extraction processes in systems solid-sub- or supercritical fluid and the development of complete separation technologies.
With regard to the already developed knowledge, rosemary extracts are being produced in industrial scale.
I. High-pressure micronisation – PGSS. With the developed technique – PGSS (Particle from Gas Saturated Solutions) we have obtained small particles of substances, which are thermally labile and liable to oxidation processes. Research was oriented towards the following:
1. Theoretical and experimental studies of thermodynamic properties of systems for high-pressure micronisation (EP 0744 922).
2. We have performed studies of phase equilibria of systems solid-gas in liquid gas. We have determined S-L-G curves of different systems dependent on pressure, gas type and the melt of the substance under investigation. Research of the influence of thermodynamic parameters and fluids dynamic parameters on the particle size and their distribution.
3. With the lab-scale equipment for micronisation, we have researched the influence of different process parameters (pre- and after expansion pressure, pre- and after expansion temperature, type of compressible media, nozzle type and the solubility of compressible media in the substance) on the particle size and their size distribution.
II. Supercritical fluids as reaction media: We have experimentally determined the influence of process parameters on the enzyme synthesis of fatty acid esters in supercritical CO2. Further research has been oriented towards the study of the use of other gasses of high density (butane, propane) as reaction media for bioreactions.
- The ractions were performed in batch high-pressure mixing reactor, where we have determined optimal process parameters, reaction kinetics and thermodynamic properties.
- The gained experimental data were used for performing the enzyme-catalyzed synthesis in the high-pressure continuous reactor, which is from the industrial-use point of view of first importance.
- At the same time, we have studied the possibility of integrating the synthesis and separation processes, which includes also experimental determinations of phase equilibria in SC systems.
Most important scientific results
Final report
Most important socioeconomically and culturally relevant results
Final report
