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Projects / Programmes source: ARIS

Joint effects of binary mixtures of cadmium, zinc and mercury on selected test animals and plants

Research activity

Code Science Field Subfield
1.03.01  Natural sciences and mathematics  Biology  Zoology and zoophysiology 
Keywords
toxicity, metals, cadmium, zinc, mercury, animals, plants
Evaluation (rules)
source: COBISS
Researchers (26)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  16039  PhD Maja Berden Zrimec  Metrology  Researcher  2002  260 
2.  21844  Gregor Bračko    Researcher  2002 - 2004  40 
3.  19945  PhD Luka Drinovec  Physics  Researcher  2002 - 2004  178 
4.  11155  PhD Damjana Drobne  Biology  Head  2002 - 2004  861 
5.  11215  PhD Samo Drobne  Geodesy  Researcher  2002 - 2004  875 
6.  03589  PhD Aleš Fajgelj  Chemistry  Researcher  2002 - 2004  76 
7.  19724  Vesna Fajon    Researcher  2002 - 2004  296 
8.  10582  PhD Ingrid Falnoga  Neurobiology  Researcher  2002 - 2004  344 
9.  05027  PhD Milena Horvat  Chemistry  Researcher  2002 - 2004  1,886 
10.  18749  PhD Rok Kostanjšek  Biology  Researcher  2002 - 2004  470 
11.  04351  PhD Bogdan Kralj  Chemistry  Researcher  2002 - 2004  131 
12.  21408  PhD Aleš Lapanje  Microbiology and immunology  Researcher  2002 - 2004  354 
13.  21244  PhD Jan Mavri  Materials science and technology  Researcher  2002 - 2004  58 
14.  08946  Silva Perko    Researcher  2002 - 2004  51 
15.  13605  PhD Simona Prevorčnik  Biology  Researcher  2002 - 2004  103 
16.  12278  PhD Maja Rupnik  Microbiology and immunology  Researcher  2002 - 2004  684 
17.  01873  PhD Vekoslava Stibilj  Chemistry  Researcher  2002 - 2004  687 
18.  07737  PhD Jasna Štrus  Biology  Researcher  2002 - 2004  443 
19.  11539  PhD Polonca Trebše  Control and care of the environment  Researcher  2002 - 2004  513 
20.  08597  Zdenka Trkov    Researcher  2002 - 2004  76 
21.  14011  PhD Dominik Vodnik  Biology  Researcher  2002 - 2004  415 
22.  21623  PhD Katarina Vogel Mikuš  Biology  Researcher  2002 - 2004  615 
23.  16065  PhD Primož Zidar  Biology  Researcher  2002 - 2004  171 
24.  16040  PhD Alexis Zrimec  Biology  Researcher  2002 - 2004  225 
25.  03950  PhD Dušan Žigon  Chemistry  Researcher  2002 - 2004  169 
26.  16381  PhD Nada Žnidaršič  Biology  Researcher  2002 - 2004  239 
Organisations (5)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0106  Jožef Stefan Institute  Ljubljana  5051606000  90,649 
2.  0431  BION Institute  Ljubljana  5376041000  280 
3.  0481  University of Ljubljana, Biotechnical Faculty  Ljubljana  1626914  66,273 
4.  0792  University of Ljubljana, Faculty of Civil and Geodetic Engineering  Ljubljana  1626981  25,714 
5.  1540  University of Nova Gorica  Nova Gorica  5920884000  14,060 
Abstract
Cadmium, zinc and mercuray have a central position in ecotoxicological studies. The mode of action of heavy metal ions is described to be dissimilar, at least at the subcellular level. Contrary to many other chemicals, the joint effects of metals in simple mixtures have strong deviations from both nonadditive and response additive effects (synergism, antagonism). In the literature, no general trend for metal joint effects can be found. There is a belief that nonaditive, synergistic or antagonistic effects depend on the metals, organisms and toxicity endpoints. Recent studies have revealed, that the type of mixture effect strongly depends on the metal concentration in the mixture. One can speculate that the type of joint effect could be predicted from the metal concentration in the mixture. The aim of our study is to find out whether a shift of the type of a metal joint effect above a certain threshold exposure level is a general trend or an exception. Recognition of the trend in metal joint effects would make a risk assessment much easier because it would allow some generalisation of toxicity data. In our work, toxicity of Cd, Zn and Hg in binary mixtures will be studied at biochemical and physiological level of two plants and two animal species, one of each is terrestrial and the other one aquatic. The two aquatic test organisms are Daphnia magna and Lemna minor, the two terrestrial test organisms are Porcellio scaber and Thlaspi praecox. Data on NOEC and LOEC for target and non-target endpoints will show the sensitivity of the endpoint. While data on ECs of single metals and that of mixtures are crucial for interpretation of the metal joint effects and subsequently for risk assessment. Laboratory data will be supplemented with field analyses of Zn, Cd and Hg. On the basis of metal concentrations in polluted environment and laboratory toxicity data, possible effects of Zn, Cd and Hg will be assessed. The need to considere metal joint effects in risk assessment will be discussed.
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