Loading...
Projects / Programmes source: ARIS

Lipid peroxidation and functional damage in target tissues and organs in citizens of Idrija and mercury miners exposed to the elemental mercury

Research activity

Code Science Field Subfield
3.07.00  Medical sciences  Metabolic and hormonal disorders   

Code Science Field
B190  Biomedical sciences  Clinical chemistry 
B370  Biomedical sciences  Endocrinology of invertebrates 
B480  Biomedical sciences  Endocrinology, secreting systems, diabetology 
Keywords
elemental mercury, antioxydants, DNA damages, melatonin, 8-OH-dG
Evaluation (rules)
source: COBISS
Researchers (17)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  18541  Matjaž Centa    Researcher  2002 - 2004 
2.  19724  Vesna Fajon    Researcher  2002 - 2004  296 
3.  10582  PhD Ingrid Falnoga  Neurobiology  Researcher  2002 - 2004  342 
4.  05027  PhD Milena Horvat  Chemistry  Researcher  2002 - 2004  1,878 
5.  14082  PhD Radojko Jaćimović  Physics  Researcher  2002 - 2004  726 
6.  17160  PhD Aleš Jerin  Cardiovascular system  Researcher  2002 - 2004  196 
7.  13425  PhD Darja Kobal Grum  Psychology  Researcher  2002 - 2004  632 
8.  15814  PhD Jože Kotnik  Geology  Researcher  2002 - 2004  386 
9.  04351  PhD Bogdan Kralj  Chemistry  Researcher  2002 - 2004  131 
10.  21839  Mladen Krsnik  Human reproduction  Researcher  2002 - 2004  179 
11.  10691  PhD Joško Osredkar  Human reproduction  Head  2002 - 2004  1,305 
12.  03279  PhD Vera Pompe-Kirn  Oncology  Researcher  2002 - 2004  365 
13.  03893  PhD Marija Prezelj  Human reproduction  Researcher  2002 - 2004  218 
14.  15443  MSc Alenka Sešek Briški  Metabolic and hormonal disorders  Researcher  2002 - 2004  102 
15.  01873  PhD Vekoslava Stibilj  Chemistry  Researcher  2002 - 2004  686 
16.  08597  Zdenka Trkov    Researcher  2002 - 2004  76 
17.  03950  PhD Dušan Žigon  Chemistry  Researcher  2002 - 2004  168 
Organisations (4)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0106  Jožef Stefan Institute  Ljubljana  5051606000  89,989 
2.  0302  Institute of Oncology Ljubljana  Ljubljana  5055733000  15,352 
3.  0312  University Medical Centre Ljubljana  Ljubljana  5057272000  76,305 
4.  0581  University of Ljubljana, Faculty of Arts  Ljubljana  1627058  97,064 
Abstract
The overall objective of the proposed study is to analyze and quantify the impact of elemental mercury (HgO) exposure on human health in occupational and ambient exposure in Idrija. The principal objective is to test hypothesis whether the accomulated level of Hg0 in previous and present occupational and ambient exposure (a) promotes lipid peroxidation, which could increase the risk of ishaemic heart disease, (b) influence on central nervous system and kidney and (c) the functional capacity of pineal, pituitary, thyroid and testes glands as a result of higher accumulation of Hg0 in these glands. The study will significantly improve the health surveillance of exposed population to Hg0 through impruved evaluation of specificity of selected bomarkers of early biological effects and initial impairment of functional capacity of target organs and tissues.
Views history
Favourite