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Projects / Programmes source: ARIS

Genetic factors and hormones in metabolic diseases

Research activity

Code Science Field Subfield
3.07.00  Medical sciences  Metabolic and hormonal disorders   

Code Science Field
B480  Biomedical sciences  Endocrinology, secreting systems, diabetology 
Keywords
osteoporosis, arthroplasty, diabetic nephropathy, insulin resistance
Evaluation (rules)
source: COBISS
Researchers (27)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  17696  Marija Bručan    Researcher  2002 - 2004 
2.  21970  Dragica Dundovič    Researcher  2002 - 2004 
3.  17697  Lea Gaspari    Researcher  2002 - 2004  11 
4.  17698  Lidija Grčar    Researcher  2002 - 2004 
5.  01900  PhD Sergej Hojker  Human reproduction  Researcher  2002 - 2004  314 
6.  01531  PhD Matija Horvat  Cardiovascular system  Researcher  2002 - 2004  289 
7.  18372  PhD Andrej Janež  Metabolic and hormonal disorders  Researcher  2002 - 2004  665 
8.  17700  Sonja Jovanovič    Researcher  2002 - 2004 
9.  03343  PhD Andreja Kocijančič  Metabolic and hormonal disorders  Head  2002 - 2004  327 
10.  17701  Slavica Kojanić    Researcher  2002 - 2004 
11.  19380  PhD Radko Komadina  Neurobiology  Researcher  2002 - 2004  486 
12.  17704  Bojana Korošec    Researcher  2002 - 2004 
13.  17703  Ivanka - Vanda Kramar    Researcher  2002 - 2004 
14.  18364  Ida Lovec    Researcher  2002 - 2004 
15.  12189  PhD Janja Marc  Metabolic and hormonal disorders  Researcher  2002 - 2004  712 
16.  01161  PhD Marko Noč  Cardiovascular system  Researcher  2002 - 2004  475 
17.  10691  PhD Joško Osredkar  Human reproduction  Researcher  2002 - 2004  1,305 
18.  18363  Sabina Podlesnik    Researcher  2002 - 2004 
19.  01989  PhD Janez Preželj  Metabolic and hormonal disorders  Researcher  2002 - 2004  303 
20.  01993  PhD Maja Ravnik-Oblak  Metabolic and hormonal disorders  Researcher  2002 - 2004  229 
21.  16358  MSc Mojca Remškar  Cardiovascular system  Researcher  2002 - 2004  28 
22.  21972  Alenka Roš    Researcher  2002 - 2004 
23.  17706  Suzana Rozman    Researcher  2002 - 2004  18 
24.  21971  Elizabeta Stepanovič    Researcher  2002 - 2004  11 
25.  06739  PhD Marjeta Tomažič  Metabolic and hormonal disorders  Researcher  2002 - 2004  113 
26.  01996  PhD Matjaž Vrtovec  Metabolic and hormonal disorders  Researcher  2002 - 2004  79 
27.  19636  Angelca Zver    Researcher  2002 - 2004 
Organisations (3)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0312  University Medical Centre Ljubljana  Ljubljana  5057272000  76,723 
2.  0787  University of Ljubljana, Faculty of Pharmacy  Ljubljana  1626973  17,540 
3.  1187  General hospital Celje  Celje  5064716  2,857 
Abstract
Our research in the field of bone pathology will be oriented toward medical intervention in patients with total hip arthroplasty. We expect to lower or even to prevent early periprosthetic bone loos observed postoperatively in these patients and so to contribute to better results of local surgical bone therapy. At the same time we will test the value of different bone metabolism and genetic markers in predicting early postoperative bone mineral density changes and/or susceptibility to medical therapy. That kind of research, focused on the local periprosthetic changes, that are known not to be dependent on the baseline bone mineral density status, has not been done yet. The second part of our project will deal with renal functional reserve as a possible early predictor of diabetic nephropathy. As endothelial dysfunction is supossed to be important in the development of diabetic nephropathy, we shall include markers of endothelial function into the models to predict the development of diabetic nephropathy. The final part of our project includes research of molecular processes of insulin resistence that seem to play pivotal role in the pathogenesis of diabetes mellitus type 2. In vitro investigations will be done on fat tissue of patients with gestational diabetes, which can serve as a human model for identifying the earliest difects in insulin action.
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