Projects / Programmes source: ARIS

Ivermectin residues in sheep plasma, milk and milk products after subcutaneous administration

Research activity

Code Science Field Subfield
4.04.05  Biotechnical sciences  Veterinarian medicine  Sanitary protection of animal origin food 

Code Science Field
B420  Biomedical sciences  Nutrition 
B750  Biomedical sciences  Veterinary medicine: surgery, physiology, pathology, clinical studies 
Ivermectin, residues, analytics, sheep, suckling lambs, milk, plasma, milk products,
Evaluation (rules)
source: COBISS
Researchers (6)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  08602  PhD Vesna Cerkvenik Flajs  Veterinarian medicine  Researcher  1998 - 1999  173 
2.  01869  PhD Darinka-Zdenka Doganoc  Veterinarian medicine  Head  1998 - 1999  152 
3.  07850  PhD Marinka Drobnič-Košorok  Veterinarian medicine  Researcher  1998 - 1999  185 
4.  00910  PhD Janez Marinšek  Veterinarian medicine  Researcher  1998 - 1999  133 
5.  01644  PhD Milan Pogačnik  Veterinarian medicine  Researcher  1998 - 1999  624 
6.  08110  PhD Ksenija Šinigoj Gačnik  Veterinarian medicine  Researcher  1998 - 1999  189 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0406  University of Ljubljana, Veterinary Faculty  Ljubljana  1627139  10,820 
Residual profile of a very effective anthelmintic ivermectin in sheep after subcutaneous administration will be investigated. Pharmacokinetics in plasma and milk will be evaluated, so the withdrawal time for milk can be established. The ivermectin transfer to suckling lambs via the milk will be investigated, too. For that purpose the plasma of the suckling lambs will be analyzed. The effect of thermal treatment and milk fermentation on ivermectin stability will be examined. Sheep milk with ivermectin residues will be heated under pasteurisation and boiling conditions. Finally, milk products such as joghurt, cheese, pot-cheese and whey will be produced. All matrixes will be analyzed by HPLC with fluorescent detection after SPE clean-up and pre- column derivatization.
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