Projects / Programmes
Ivermectin residues in sheep plasma, milk and milk products after subcutaneous administration
Code |
Science |
Field |
Subfield |
4.04.05 |
Biotechnical sciences |
Veterinarian medicine |
Sanitary protection of animal origin food |
Code |
Science |
Field |
B420 |
Biomedical sciences |
Nutrition |
B750 |
Biomedical sciences |
Veterinary medicine: surgery, physiology, pathology, clinical studies |
Ivermectin, residues, analytics, sheep, suckling lambs, milk, plasma, milk products,
Researchers (6)
Organisations (1)
Abstract
Residual profile of a very effective anthelmintic ivermectin in sheep after subcutaneous administration will be investigated. Pharmacokinetics in plasma and milk will be evaluated, so the withdrawal time for milk can be established. The ivermectin transfer to suckling lambs via the milk will be investigated, too. For that purpose the plasma of the suckling lambs will be analyzed.
The effect of thermal treatment and milk fermentation on ivermectin stability will be examined. Sheep milk with ivermectin residues will be heated under pasteurisation and boiling conditions. Finally, milk products such as joghurt, cheese, pot-cheese and whey will be produced.
All matrixes will be analyzed by HPLC with fluorescent detection after SPE clean-up and pre- column derivatization.