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Projects / Programmes source: ARIS

Aplikativna in bazična fiziologija in patofiziologija v medicini (Slovene)

Periods
Research activity

Code Science Field Subfield
3.03.00  Medical sciences  Neurobiology   
3.06.00  Medical sciences  Cardiovascular system   

Code Science Field
B7   Biomedical sciences  B7  
B640  Biomedical sciences  Neurology, neuropsychology, neurophysiology 
B530  Biomedical sciences  Cardiovascular system 
B220  Biomedical sciences  Genetics, cytogenetics 

Code Science Field
3.01  Medical and Health Sciences  Basic medicine 
Evaluation (rules)
source: COBISS
Researchers (49)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  13672  PhD Igor Bartenjev  Microbiology and immunology  Researcher  2009 - 2014  293 
2.  20471  Dejan Bregar    Technical associate  2009 - 2014  10 
3.  24927  PhD Miran Brvar  Neurobiology  Researcher  2009 - 2014  601 
4.  27580  PhD Klara Bulc Rozman  Neurobiology  Researcher  2009 - 2014  19 
5.  15667  PhD Matjaž Bunc  Neurobiology  Researcher  2009 - 2014  530 
6.  15243  PhD Ksenija Cankar  Cardiovascular system  Researcher  2009 - 2014  250 
7.  10779  PhD Rok Černe  Neurobiology  Researcher  2009 - 2011  39 
8.  26267  Manja Dolinar    Technical associate  2009 - 2014 
9.  08797  MSc Tatjana Drglin  Cardiovascular system  Technical associate  2010 - 2014  33 
10.  27577  PhD Andrej Fabjan  Neurobiology  Researcher  2012 - 2014  57 
11.  05232  PhD Žarko Finderle  Cardiovascular system  Researcher  2009 - 2014  158 
12.  21903  Alenka Frangež Štrukelj    Technical associate  2009 - 2014 
13.  18266  Nada Godnič    Technical associate  2009 - 2011 
14.  29980  PhD Igor Darko Gregorič  Neurobiology  Researcher  2009 - 2014  206 
15.  36087  Manja Hribar  Stomatology  Technical associate  2013 - 2014  32 
16.  15169  PhD Damijana Mojca Jurič  Neurobiology  Researcher  2009 - 2014  103 
17.  35358  Maja Justin  Neurobiology  Junior researcher  2012 - 2014 
18.  16344  PhD Borut Kirn  Cardiovascular system  Researcher  2009 - 2014  62 
19.  17175  PhD Igor Kocijančič  Neurobiology  Researcher  2009 - 2014  100 
20.  27916  PhD Marjan Koršič  Neurobiology  Researcher  2009 - 2014  197 
21.  18322  PhD Helena Lenasi  Cardiovascular system  Researcher  2009 - 2014  186 
22.  29610  PhD Mitja Letonja  Cardiovascular system  Researcher  2009 - 2014  55 
23.  24351  Mitja Maružin  Neurobiology  Technical associate  2009 - 2010  12 
24.  05922  PhD Živa Melik  Cardiovascular system  Researcher  2009 - 2014  107 
25.  22642  Vesna Metelan    Technical associate  2009 - 2014 
26.  18825  PhD Irina Milisav Ribarič  Neurobiology  Researcher  2009 - 2014  154 
27.  18549  PhD Aleksandra Milutinović Živin  Cardiovascular system  Researcher  2009 - 2014  125 
28.  01984  Martin Možina  Neurobiology  Technical associate  2009 - 2011  228 
29.  28326  PhD Damijan Nipič  Microbiology and immunology  Junior researcher  2009 - 2010  16 
30.  21413  PhD Damjan Osredkar  Human reproduction  Researcher  2014  483 
31.  08223  Daniel Peterec  Cardiovascular system  Technical associate  2009 - 2014  30 
32.  35892  Tina Pintar Tratnik    Technical associate  2013 - 2014 
33.  08993  PhD Marko Potočnik  Public health (occupational safety)  Researcher  2009 - 2014  252 
34.  05201  PhD Nejka Potočnik  Cardiovascular system  Researcher  2009 - 2014  136 
35.  24561  PhD Urška Puh  Neurobiology  Researcher  2009 - 2014  372 
36.  35604  Renata Radič Berglez    Technical associate  2012 - 2014 
37.  35603  Tina Robida    Technical associate  2012 - 2014  16 
38.  28168  Polona Sajovic    Technical associate  2011 - 2014 
39.  36102  PhD Vladka Salapura  Medical sciences  Researcher  2014  275 
40.  02020  PhD Radovan Starc  Neurobiology  Researcher  2009 - 2014  192 
41.  04341  PhD Vito Starc  Cardiovascular system  Researcher  2009 - 2014  270 
42.  09557  PhD Martin Štrucl  Cardiovascular system  Researcher  2009 - 2014  157 
43.  07002  PhD Dušan Šuput  Neurobiology  Head  2009 - 2014  434 
44.  29977  Daša Šuput Skvarča  Microbiology and immunology  Technical associate  2012  18 
45.  18268  Danica Šurev    Technical associate  2009 - 2014 
46.  26268  PhD Andrej Vovk  Neurobiology  Researcher  2009 - 2014  52 
47.  28076  PhD Matej Vrabec  Medical sciences  Researcher  2011 - 2012  21 
48.  18826  PhD Bojan Vrtovec  Medical sciences  Researcher  2009 - 2014  487 
49.  07797  PhD Rudolfina Zorc-Pleskovič  Cardiovascular system  Researcher  2009 - 2014  138 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0381  University of Ljubljana, Faculty of Medicine  Ljubljana  1627066  48,407 
Significance for science
The most important role of the programme P3-0019 for the development of science is its interdisciplinarity. We have combined the research on molecular, genetic, cellular and clinical level leading to the translational science in medicine in the interconnected field(s) of neuroscience, neurovascular coupling and cardiovascular medicine. Here are some representative examples: New inhibitor of AChE and blocker of nAChR has been discovered and synthetic analogues synthetized. These substances may be important in the development of drugs targeting at a) dementias and b) treatment of addictions. Neurodegenerative effects of microcystins, a naturally occurring toxins have been discovered. New methods for brain segmentations have been developed and used in the study of brain plasticity, e.g. in deaf subjects (absence of auditory output results in widespread structural brain changes). The ionic basis of the vasoactive intestinal peptide caused arrhythmias has been elucidated. As most of the studied pathology can be linked to the damage by the reactive oxidative species leading to apoptosis the latter process has been studied in detail. We have demonstrated that the early stages of apoptosis are, contrary to our previous knowledge, reversible. This is an important discovery that will be studied in the future in combination with the study of cell senescence.
Significance for the country
Integration of research »from molecule to man« in the field(s) of neuroscience, neurovascular coupling and cardiovascular medicine is important for affirmation of translational medicine in Slovenia. Together with scientists in Slovenia and abroad (France, USA) we have developed several procedures useful for scientific research as well as for the clinical practice. Public awareness of the importance of the research is tightly related to the transfer of knowledge into the every day’s practice. Here are some examples of achievements with socio-economic impact: Our group was the first in Slovenia to introduce whole body DWI and also the first to introduce pudendal nerve MR imaging in the diagnostics of pelvic anomalies. Research of the influence of the laminar flow on endothelial function has contributed to the introduction of the new generation of the left ventricular assist devices. Development of EKG and high-resolution EKG analysis has led to US patent. Carbon monoxide poisoning is relatively frequent in Slovenia. In the field of hyperbaric medicine we have shown that only hyperbaric oxygen and not 100 % oxygen at atmospheric pressure can prevent neuronal apoptosis after carbon monoxide intoxication. Two members of the team have achieved exceptional results in the treatment of cardiovascular diseases: introduction of transcutaneous aortic valve replacement and treatment of cardiomyopathies with trans-epicardial application of CD34+ cells.
Audiovisual sources (1)
no. Title (with video link) Event Source
1. Aplikativna in bazična fiziologija in patofiziologija v medicini (Slovene)  Promotional video of research programme on Videolectures  Research programme video presentation 
Most important scientific results Annual report 2009, 2010, 2011, 2012, 2013, final report, complete report on dLib.si
Most important socioeconomically and culturally relevant results Annual report 2009, 2010, 2011, 2012, 2013, final report, complete report on dLib.si
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