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Projects / Programmes source: ARIS

Indeks CD64 in CD163 na levkocitih, sprožilni (triggering) receptor izražen na monocitih (TREM-1) , beljakovina, ki veže lipopolisaharid (LBP) ter protitelesa proti endotoksinu ( EndoCab) pri sepsi in pljučnici kritično bolnih otrok. (Slovene)

Research activity

Code Science Field Subfield
3.05.00  Medical sciences  Human reproduction   

Code Science Field
3.02  Medical and Health Sciences  Clinical medicine 
Evaluation (rules)
source: COBISS
Researchers (11)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  02148  PhD Metka Derganc  Human reproduction  Head  2009 - 2012  452 
2.  28445  PhD Urška Glinšek Biškup  Microbiology and immunology  Researcher  2010  36 
3.  15706  PhD Tanja Gmeiner  Pharmacy  Researcher  2009 - 2011  146 
4.  24670  PhD Mojca Grošelj Grenc  Human reproduction  Researcher  2009 - 2012  172 
5.  10337  PhD Alojz Ihan  Microbiology and immunology  Researcher  2009  1,442 
6.  19257  PhD Lidija Kitanovski  Oncology  Researcher  2009 - 2012  152 
7.  25991  PhD Andreja Nataša Kopitar  Microbiology and immunology  Researcher  2009  188 
8.  10691  PhD Joško Osredkar  Human reproduction  Researcher  2009 - 2012  1,305 
9.  22349  PhD Maja Pavčnik Arnol  Human reproduction  Researcher  2009 - 2012  157 
10.  24666  Mirjana Petreska    Technical associate  2009 - 2012 
11.  14504  PhD Katja Seme  Microbiology and immunology  Researcher  2009  701 
Organisations (2)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0312  University Medical Centre Ljubljana  Ljubljana  5057272000  76,699 
2.  0381  University of Ljubljana, Faculty of Medicine  Ljubljana  1627066  47,545 
Significance for science
Results of the project group are a contribution to the development of science: in the early diagnosis of sepsis in critically ill newborns in children surface antigens index iCD64 in neutrophils proved to be most reliable in children while LBP was best in newborns; in the field of improving diagnosis of pneumonia in critically ill newborns and children the most important serum marker was iCD64 on neutrophils, while PCT and LBP were less reliable; in the field of diagnosing sepsis in children with febrile neutropenia and cancer, LBP, PCT and CRP had similar, intermediate accuracy, Il-6 was the earliest; in PPROM of premature infants high concentration of defensins, but not IL-6 in the vaginal fluid was correlated to fetal/neonatal inflammation and neurological derangement at one year of age; In PPROm of premature infants LBP in the umbilical cord blood and on the first day of life was correlated to fetal/neonatal inflammation and neurological derangement at one year of age; In the diagnosis of postoperative infection in newborns, IL-8 decreases most rapidly after surgery and raises again as a sign of infection, PCT in the first days of life is very variable
Significance for the country
Three publications in medical journals indexed by SCI represent promotion of Slovenian medical science, two papers have been submitted to journals with SCI; One doctors thesis has been defended in 2012; the second is in the phase of presentation of results. The two new doctors of science will contribute to the medical research community. We expect that a more reliable diagnosis of severe infection in children with different diseases will contribute to a more rational use of antibiotics which will be not only economical but will also prevent development of resistant bacterial strains.
Most important scientific results Annual report 2009, 2010, 2011, final report, complete report on dLib.si
Most important socioeconomically and culturally relevant results Annual report 2009, 2010, 2011, final report, complete report on dLib.si
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