Projects / Programmes
Prediction of preterm and prevention of very preterm delivery
| Code |
Science |
Field |
Subfield |
| 3.05.00 |
Medical sciences |
Human reproduction |
|
| Code |
Science |
Field |
| B570 |
Biomedical sciences |
Obstetrics, gynaecology, andrology, reproduction, sexuality |
preterm delivery, very preterm delivery, risk factors, model for prediction, ultrasound markers, biochemical markers, clinical markers, psychological stress, socio-economical factors
Researchers (18)
Organisations (1)
Abstract
Preterm delivery (PTD) is the most frequent disease in pregnancy and forms 80 % of perinatal morbidity and mortality. Depending on the intensive therapy and care facilities, survival is better as gestational age increases. One should be very careful when interpreting results, as during the last decades there has been a shift in the time of death from the early to the late neonatal period. PTD has not decreased during the last decade, in spite of all known risk factors. It is necessary to actively search for women/pregnant women with known risk factors and implement effective procedures. The consequences of VPTD (below 32 weeks) for children are extremely serious, and very preterm neonates might suffer from them their whole lifes. They also present an extremely large economical burden. The extremely preterm neonates e.g. those after only 24 weeks of gestation, might stay in NICU for 90 days and each day costs app 750 EUR. Distinction between VPTD below 32 weeks and PTD from 33 to 36 completed weeks should be done. The goal is to elaborate the model for prediction of preterm delivery and find women/pregnant women with risk factors after which implementation of all known methods to prolong pregnancy should follow. Risk factors are found by medical, social and psychological history taking, ultrasound and biochemical markers and clinical evaluation. Implementation of effective procedures should lower the VPTD rate.
