Projects / Programmes
Cellular and tissue engineering
Code |
Science |
Field |
Subfield |
2.06.00 |
Engineering sciences and technologies |
Systems and cybernetics |
|
Code |
Science |
Field |
B001 |
Biomedical sciences |
General biomedical sciences |
B002 |
Biomedical sciences |
Biophysics |
wound healing, anti-tumor electrotherapy, near-infrared spectroscopy (NIRS), interstitial fluid pressure (IFP), modeling, electrical stimulation, electroporation, electric current, oxigenation, wounds, neoplasms
Researchers (12)
Organisations (1)
Abstract
The project focuses on the impact of electric fields and currents on wound healing and their anticancer effects. In the field of wound healing, we continue the existing study, but our attention is now focused on investigation of individual components of the healing process. In the field of antitumor therapy with electric currets, we study the effectiveness of AC in comparison with DC and rectangular pulsed currents, which are currently used for therapy. In addition, we study the impact of electric currents on the interstitial fluid pressure (IFP). For the study of effects of different electrical treatments and stimulation on perfusion and oxygenation of tumors and soft tissue in lower extremities, we use the modern noninvasive method of near-infrared spectroscopy (NIRS). Development of mathematical models gives us an additional insight into the processes of in vitro and in vivo experiments. Within the project, we are also developing an expert system for prediction of wound healing process.