Projects / Programmes
Interakcije Hg in Cd z lipoproteini, liposomskimi membranami, selenom in metalotioneini (Slovene)
Code |
Science |
Field |
Subfield |
3.03.00 |
Medical sciences |
Neurobiology |
|
Code |
Science |
Field |
P340 |
Natural sciences and mathematics |
Lipids, steroids, membranes |
P360 |
Natural sciences and mathematics |
Inorganic chemistry |
Hg, Cd, Se, metallothioneins, lipoproteins, liposome membranes, interactions
Researchers (9)
no. |
Code |
Name and surname |
Research area |
Role |
Period |
No. of publicationsNo. of publications |
1. |
10582 |
PhD Ingrid Falnoga |
Medical sciences |
Researcher |
1999 - 2001 |
335 |
2. |
05027 |
PhD Milena Horvat |
Natural sciences and mathematics |
Researcher |
1999 - 2001 |
1,820 |
3. |
00412 |
PhD Igor Križaj |
Natural sciences and mathematics |
Researcher |
1999 - 2001 |
698 |
4. |
18288 |
PhD Martina Logar |
Natural sciences and mathematics |
Researcher |
1999 - 2001 |
155 |
5. |
00393 |
PhD Milan Valter Schara |
Natural sciences and mathematics |
Researcher |
1999 - 2001 |
343 |
6. |
01352 |
PhD Peter Stegnar |
Natural sciences and mathematics |
Principal Researcher |
1999 - 2001 |
275 |
7. |
01873 |
PhD Vekoslava Stibilj |
Natural sciences and mathematics |
Researcher |
1999 - 2001 |
686 |
8. |
01411 |
PhD Zdenka Šlejkovec |
Natural sciences and mathematics |
Researcher |
1999 - 2001 |
237 |
9. |
13786 |
Borut Štefanič |
Medical sciences |
Researcher |
1999 - 2001 |
61 |
Organisations (2)
Abstract
Cadmium and mercury ions can act as neurotoxins and are probably involved in the pathogenesis of some brain dysfunctions like Alzheimer''s disease and age senility. The investigation will be focused on interactions of inorganic mercury with biological macromolecules (lipoproteins, liposomes) with respect to the induced changes in their structural organization and the involvement of mercury in lipid peroxidation. In human tissue samples (thyroid, brain tissues) with elevated levels of toxic trace elements (Hg, Cd) the study will be concentrate on the cellular distribution of these elements, their binding to low molecular weight protective proteins, i.e. metallothioneins and selenium coaccumulation.