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Projects / Programmes source: ARIS

EMG diagnostic method to assess uterine cervix smooth muscle activity

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Research activity

Code Science Field Subfield
3.05.00  Medical sciences  Human reproduction   

Code Science Field
B570  Biomedical sciences  Obstetrics, gynaecology, andrology, reproduction, sexuality 
Keywords
uterus, cervix, smooth muscle, EMG, diagnostics,pregnancy, labour, pre-term labour, tocolytics, electrical stimulation, animal model, ovca; data base
Evaluation (rules)
source: COBISS
Evaluation of bibliographic research performance indicators according to ARIS methodology
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Researchers (13)
no. Code Name and surname Research area Role Period No. of publications
1.  02204  PhD Karel Flisar  Systems and cybernetics  Researcher  2005 - 2007  73 
2.  14772  PhD Tomaž Jarm  Systems and cybernetics  Researcher  2008  213 
3.  19426  MSc Gorazd Kavšek  Human reproduction  Junior researcher  2005 - 2008  102 
4.  15675  PhD Tadej Kotnik  Systems and cybernetics  Researcher  2005 - 2007  206 
5.  23976  PhD Peter Kramar  Metrology  Researcher  2005 - 2007  179 
6.  15355  PhD Branimir Leskošek  Public health (occupational safety)  Researcher  2005 - 2008  182 
7.  12537  PhD Alenka Maček - Lebar  Systems and cybernetics  Head  2005 - 2008  223 
8.  20396  Darko Oberžan    Technical associate  2005 - 2008  0 
9.  02750  PhD Marjan Pajntar  Human reproduction  Researcher  2005 - 2008  331 
10.  11621  MSc Stanko Pušenjak  Human reproduction  Researcher  2005 - 2008  80 
11.  03410  PhD Drago Rudel  Medical sciences  Researcher  2005 - 2008  193 
12.  05015  PhD Ivan Verdenik  Human reproduction  Researcher  2005 - 2008  480 
13.  17837  PhD Gaj Vidmar  Systems and cybernetics  Researcher  2005 - 2008  552 
Organisations (4)
no. Code Research organisation City Registration number No. of publications
1.  0312  University Medical Centre Ljubljana  Ljubljana  5057272000  77,480 
2.  0381  University of Ljubljana, Faculty of Medicine  Ljubljana  1627066  48,255 
3.  0436  MKS Electronic Systems  Ljubljana  5308194000  208 
4.  1538  University of Ljubljana, Faculty of Electrical Engineering  Ljubljana  1626965  27,774 
Abstract
A mechanism of the uterine cervix smooth muscle activity will be studied in humans and in an animal model (gravid instrumented sheep) aiming at helping those women who come to a hospital due to a threatened pre-term labour or having difficulties at the term labour. As the activity of the uterine smooth muscles may be monitored by recording electromyographic (EMG) activity, most of research groups around the world pay their attention to the uterine corpus. Our group has been oriented towards the cervix and its role in preterm labour and long-lasting or delayed labours at term. Beside the improvement in general understanding of mechanisms influencing the process of pregnancy and labour, the objective of the project is to design a diagnostic device to indicate early pathological changes in the cervix that may leed to an unwanted outcome. Our hypothesis is that we could detect early changes in uterine EMG activity and thus give an obstretitian additional decision-making tool to influence the process by using adequate therapy. Spontaneous EMG activity will be recorded in sheep during pregnancy. To learn more from the animal model we’ll modulate EMG activity by application of tocolitics and/or electrical stimulation. At labour EMG will be recorded in sheep and in humans. To efficiently test EMG processing algorithms an international web database will be created to which international research community will contribute their EMG records gathered in different settings and models. The project should resulted in a pre-production prototype of a diagnostic device.
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