Projects / Programmes
Bioinorganic and bioorganic chemistry
January 1, 2004
- December 31, 2008
Code |
Science |
Field |
Subfield |
1.04.00 |
Natural sciences and mathematics |
Chemistry |
|
Code |
Science |
Field |
P360 |
Natural sciences and mathematics |
Inorganic chemistry |
bioactive metal complexes, metals in the environment, materials for biosensors, biomimetics, fluorination, iodination, perfluoro solvents
Researchers (23)
Organisations (2)
Abstract
New platinum coordination compounds will be prepared reacting cis-diamindichloroplatinum(II) and haloplatinates with organic ligands. Interactions of metal ions with biological macromolecules will be studied by quantummechanical modeling and the results compared with EXAFS measurements. Thin films appropriate for sensors will be developed. The mechanisms of halogen introduction into organic molecules and their influence on biological activity of new molecules will be studied.
Significance for science
The two main parts of the programme, bioinorganic and bioorganic, followed the priorities, that were defined in 6. framework programme of European community. Biomimetic models of metal ions interactions with organic molecules, and syntheses of new metal complexes with biological activity belong to nr.1 and nr.2 priorities: »Health« and »Food, agriculture, biotechnology«. Of special importance is the binding of metal ions to prion proteins and the preparation od new bioactive metal complexes, the first one to clarify prion diseases, the second one for progress of chemotherapy. Catalytic and photocatalytic metal oxides belong to priority nr. 4: »Nanoscience, nanotechnolgies, materials and new technologies« and to priority nr. 6: »Environment«. Identification of toxic metal species in environment and their immobilization belong to priority nr. 6 too. The bioorganic part as a whole follows the mentioned priorities, with a strong orientation to green chemistry.
Significance for the country
The programme represents an important contribution to sustainable development of Slovenia. The importance of the programme for Slovenia´s socio-economic and cultural development are: • a new kowledge and education of top inorganic and organic chemists • contribution to benign chemistry processes, which are friendly to the nature • elaboration of procedures important for preservation of cultural heritage of Slovenia • implementation of sustainable environmental technologies
Most important scientific results
Final report,
complete report on dLib.si
Most important socioeconomically and culturally relevant results
Final report,
complete report on dLib.si