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Projects / Programmes source: ARIS

Bioinorganic and bioorganic chemistry

Periods
Research activity

Code Science Field Subfield
1.04.00  Natural sciences and mathematics  Chemistry   

Code Science Field
P360  Natural sciences and mathematics  Inorganic chemistry 
Keywords
bioactive metal complexes, metals in the environment, materials for biosensors, biomimetics, fluorination, iodination, perfluoro solvents
Evaluation (rules)
source: COBISS
Researchers (23)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  00190  PhD Jurij Brenčič  Chemistry  Researcher  2004 - 2007  241 
2.  03440  PhD Nataša Bukovec  Chemistry  Researcher  2004 - 2008  351 
3.  03439  PhD Peter Bukovec  Chemistry  Head  2004 - 2008  544 
4.  16256  PhD Romana Cerc Korošec  Chemistry  Researcher  2004 - 2008  343 
5.  19050  Damjan Erčulj    Technical associate  2004 - 2008 
6.  18194  PhD Vojmir Francetič  Chemistry  Researcher  2004  76 
7.  12075  PhD Sabina Grabner  Chemistry  Researcher  2004 - 2008  49 
8.  14680  PhD Jernej Iskra  Chemistry  Researcher  2004 - 2008  398 
9.  19177  PhD Marjan Jereb  Chemistry  Researcher  2004 - 2008  159 
10.  20210  PhD Petra Kralj  Pharmacy  Junior researcher  2004 - 2006  15 
11.  21626  Urška Levec Jazbinšek    Technical associate  2005 - 2008 
12.  12276  PhD Barbara Modec  Chemistry  Researcher  2004 - 2008  303 
13.  25654  PhD Jasminka Pavlinac  Chemistry  Junior researcher  2005 - 2008  18 
14.  25633  PhD Ajda Podgoršek Berke  Chemistry  Junior researcher  2005 - 2008  60 
15.  24300  PhD Igor Pravst  Public health (occupational safety)  Junior researcher  2008  317 
16.  17143  Zdenka Sakelšek    Technical associate  2004 - 2008 
17.  26547  PhD Gaj Stavber  Chemistry  Junior researcher  2008  58 
18.  06058  PhD Stojan Stavber  Chemistry  Researcher  2004 - 2008  310 
19.  27823  PhD Jerneja Šauta Ogorevc  Chemistry  Junior researcher  2008  14 
20.  16025  PhD Elizabeta Tratar Pirc  Chemistry  Researcher  2004 - 2008  126 
21.  01317  PhD Marko Andrej Zupan  Chemistry  Researcher  2004 - 2008  459 
22.  16026  PhD Marija Zupančič  Chemistry  Researcher  2004 - 2008  139 
23.  24278  PhD Katja Žmitek  Public health (occupational safety)  Junior researcher  2005 - 2008  167 
Organisations (2)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0103  University of Ljubljana, Faculty of Chemistry and Chemical Technology  Ljubljana  1626990  23,072 
2.  0106  Jožef Stefan Institute  Ljubljana  5051606000  90,664 
Abstract
New platinum coordination compounds will be prepared reacting cis-diamindichloroplatinum(II) and haloplatinates with organic ligands. Interactions of metal ions with biological macromolecules will be studied by quantummechanical modeling and the results compared with EXAFS measurements. Thin films appropriate for sensors will be developed. The mechanisms of halogen introduction into organic molecules and their influence on biological activity of new molecules will be studied.
Significance for science
The two main parts of the programme, bioinorganic and bioorganic, followed the priorities, that were defined in 6. framework programme of European community. Biomimetic models of metal ions interactions with organic molecules, and syntheses of new metal complexes with biological activity belong to nr.1 and nr.2 priorities: »Health« and »Food, agriculture, biotechnology«. Of special importance is the binding of metal ions to prion proteins and the preparation od new bioactive metal complexes, the first one to clarify prion diseases, the second one for progress of chemotherapy. Catalytic and photocatalytic metal oxides belong to priority nr. 4: »Nanoscience, nanotechnolgies, materials and new technologies« and to priority nr. 6: »Environment«. Identification of toxic metal species in environment and their immobilization belong to priority nr. 6 too. The bioorganic part as a whole follows the mentioned priorities, with a strong orientation to green chemistry.
Significance for the country
The programme represents an important contribution to sustainable development of Slovenia. The importance of the programme for Slovenia´s socio-economic and cultural development are: • a new kowledge and education of top inorganic and organic chemists • contribution to benign chemistry processes, which are friendly to the nature • elaboration of procedures important for preservation of cultural heritage of Slovenia • implementation of sustainable environmental technologies
Most important scientific results Final report, complete report on dLib.si
Most important socioeconomically and culturally relevant results Final report, complete report on dLib.si
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