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Projects / Programmes source: ARIS

Periodontal Medicine

Periods
Research activity

Code Science Field Subfield
3.02.00  Medical sciences  Stomatology   

Code Science Field
B730  Biomedical sciences  Odontology, stomatology 
Keywords
periodontal medicine, periodontal disease, diabetes, cardiovascular disease, pulomonary disease, artritis, stres, MRI, subtraction radiography, antioxidants, lasers, Papillon-Lefevre sy, orthodontics, NO,epidemiology, oral health, children, adolescents
Evaluation (rules)
source: COBISS
Researchers (14)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  18079  PhD Martina Drevenšek  Stomatology  Researcher  2007 - 2008  210 
2.  01544  PhD Franc M. Farčnik  Stomatology  Researcher  2004 - 2006  218 
3.  19210  PhD Rok Gašperšič  Stomatology  Researcher  2004 - 2008  261 
4.  12446  PhD Boris Gašpirc  Stomatology  Researcher  2008  165 
5.  26270  Martina Kajzer    Technical associate  2005 - 2008 
6.  08183  PhD Narcisa-Cecilij Košir  Stomatology  Researcher  2004 - 2006  77 
7.  09290  PhD Marija Kovač-Kavčič  Stomatology  Researcher  2004 - 2008  45 
8.  29113  Mateja Lunar    Technical associate  2007 - 2008 
9.  00965  PhD Maja Ovsenik  Stomatology  Researcher  2004 - 2008  488 
10.  07625  PhD Milan Petelin  Stomatology  Researcher  2004 - 2008  243 
11.  28511  PhD Alja Plut  Stomatology  Junior researcher  2007 - 2008  28 
12.  18401  Zinka Rodman    Technical associate  2005 - 2008 
13.  26485  PhD Eva Skalerič  Stomatology  Junior researcher  2007 - 2008  41 
14.  03370  PhD Uroš Skalerič  Stomatology  Head  2004 - 2008  511 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0312  University Medical Centre Ljubljana  Ljubljana  5057272000  77,953 
Abstract
In research program the natural progression of periodontal disease in 20 year period and influence of the long standing chronic infection in periodontal tissues on the development of some systemic diseases such as cardiovascular disease, diabetes, arthritis and pneumonia will be studied. In the frame of the research program the evaluation of the periodontal wound and the influence of periodontal treatment on improvement of cardiovascular disease and diabetes will be evaluated. The prevalence of caries and periodontal disease in patients with special needs and role of NO on bone remodeling during the orthodontic treatment will be studied. In addition the role of the gene for cathepsin C in Papillon-Lefevre syndrom and influence of periodontal inflammation on activation of hypothalamo-hypophise-suprarenal axis will be studied. In therapeutic part of the program the use of pulse Er-YAG laser for periodontal surgery and the use of local subgingival delivery of antioxidant enzymes for treatment of periodontal inflammation will be evaluated.
Significance for science
Result of research program revealed the prevalence of periodontal disease among 35-85 year-old citizens of Ljubljana. The results will be used for planing of preventive and curative periodontal measures among citiziens of Ljubljana and Slovenia. The results about the role of viruses, oxygen free radicals and neurogenic components in peridontal inflammation contributed to better understanding of etiopathogenesis of periodontal disease and are important contributions to international research community. Treatment of periodontal disease in diabetes patients demontrated that subgingival application of minocycline and the use of full- mouth desinfection method significantly improve periodontal conditions and metabolic control of diabetes. In the field of periodontal surgery we were the first to demonstrate the use of Er:YAG laser and longitudinal successl in treatment of periodontal disease.
Significance for the country
The results of the research program are important for Slovenia as we demontrated the prevalence of periodontal disease and treatment needs among adult citiziens of Ljubljana. The results imply the need for more efficient preventive measure and great need for periodontal treatment among dentists and periodontists. The results of periodontal survey also imply the need for introduction of dental hygienists in oral care of Slovenia. The results of the research program also demontrated that the diabetes patients are the risk population for development of periodontal disease. Results demonstrated that diabetes patients need priority dental and periodontal treatment which contribute to improvement of metabolic control and delay of complications in diabetes patients. The use of modern technology like Er:YAG laser put Slovenia on the international top of the use of high technology in treatment of periodontal disease.
Most important scientific results Final report, complete report on dLib.si
Most important socioeconomically and culturally relevant results Final report, complete report on dLib.si
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