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Projects / Programmes source: ARIS

Optimization of human nutrition: polyphenols and bioavailability

Research activity

Code Science Field Subfield
4.03.00  Biotechnical sciences  Plant production   

Code Science Field
B420  Biomedical sciences  Nutrition 
P004  Natural sciences and mathematics  Biochemistry, Metabolism 
Keywords
safety nutrition, polyphenols, bioavailability, molecular mechanisms
Evaluation (rules)
source: COBISS
Researchers (4)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  17919  PhD Dejan Bavčar  Plant production  Researcher  2005 - 2007  296 
2.  07906  PhD Mitja Kocjančič  Chemistry  Researcher  2005 - 2007  232 
3.  25795  PhD Klemen Lisjak  Plant production  Junior researcher  2005 - 2007  322 
4.  21399  PhD Andreja Vanzo  Plant production  Head  2005 - 2007  249 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0401  Agricultural institute of Slovenia  Ljubljana  5055431  20,024 
Abstract
Polyphenols are the most abundant antioxidants in our diet. Fruit and vegetables are a rich source of polyphenols. Besides their role in the biotechnological quality, interest, however, has recently increased greatly due to their antioxidant and free-radical scavenging properties. Numerous studies have suggested that polyphenols are protective against a number of diseases caused by oxidative stress. The oxidative damage is considered to play a causative role in aging and several affections, such as cardiovascular, neurodegenerative diseases, cancer, inflammation, osteoporosis and others. Because of the limits of our endogenous defense systems and some physiopathological conditions (UV radiation, air pollutants etc.), dietary polyphenols could diminish the cumulative effects of oxidative damage over the life-span. However, the data about the bioavailability and the fate of polyphenols and the organism are still very limited; nonetheless, there is a considerable interest of many research groups in the world. The rationale of our work is to study the bioavailability of polyphenols from grape and wine in mammals. Food rich in polyphenols may be beneficial to human health and shall be widely used in pharmaceutical, food and cosmetic industry as well as in medicine in the future.
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