Projects / Programmes source: ARIS

Biotehnologija in sistemska biologija rastlin (Slovene)

Research activity

Code Science Field Subfield
4.06.00  Biotechnical sciences  Biotechnology   
1.03.00  Natural sciences and mathematics  Biology   
1.05.00  Natural sciences and mathematics  Biochemistry and molecular biology   
4.03.00  Biotechnical sciences  Plant production   

Code Science Field
4.04  Agricultural and Veterinary Sciences  Agricultural biotechnology 
Evaluation (rules)
source: COBISS
Researchers (43)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  36320  PhD Špela Alič  Biology  Junior researcher  2013 - 2014  75 
2.  19116  PhD Špela Baebler  Biotechnology  Researcher  2009 - 2014  306 
3.  29489  PhD Mirjana Bistan Žist  Microbiology and immunology  Researcher  2014  52 
4.  37410  PhD Alexandra Bogožalec Košir  Biology  Junior researcher  2014  83 
5.  27502  PhD Meti Buh Gašparič  Biotechnology  Junior researcher  2009 - 2012  46 
6.  35385  PhD Marko Chersicola  Biotechnology  Junior researcher  2012 - 2014  19 
7.  34130  PhD Anna Coll Rius  Biochemistry and molecular biology  Researcher  2012 - 2014  160 
8.  28333  PhD Urška Čepin  Biotechnology  Researcher  2009 - 2012  50 
9.  08280  PhD Marina Dermastia  Biology  Researcher  2009 - 2014  864 
10.  29616  PhD David Dobnik  Biotechnology  Researcher  2009 - 2014  295 
11.  23611  PhD Tanja Dreo  Biotechnology  Researcher  2009 - 2014  492 
12.  29650  PhD Jana Erjavec  Biotechnology  Junior researcher  2009 - 2014  38 
13.  25974  PhD Cene Gostinčar  Biotechnology  Researcher  2014  325 
14.  12688  PhD Kristina Gruden  Biotechnology  Researcher  2009 - 2014  977 
15.  27827  PhD Jon Gutierrez Aguirre  Biotechnology  Researcher  2009 - 2014  359 
16.  36481  PhD Sabina Horvat  Microbiology and immunology  Junior researcher  2013 - 2014  20 
17.  23606  PhD Matjaž Hren  Biology  Researcher  2009  114 
18.  25523  PhD Polona Kogovšek  Biology  Researcher  2009 - 2014  211 
19.  37409  PhD Maja Križnik  Biotechnology  Junior researcher  2014  41 
20.  35384  PhD Denis Kutnjak  Biotechnology  Junior researcher  2012 - 2014  264 
21.  33225  PhD Ana Lazar  Plant production  Junior researcher  2010 - 2014  29 
22.  36323  PhD Tjaša Lukan  Biology  Junior researcher  2013 - 2014  118 
23.  18344  Lidija Matičič    Technical associate  2009  41 
24.  23610  PhD Nataša Mehle  Biotechnology  Technical associate  2012 - 2014  514 
25.  29178  PhD Dany Morisset  Biotechnology  Researcher  2009 - 2013  121 
26.  29598  PhD Petra Nikolić  Biochemistry and molecular biology  Junior researcher  2009 - 2011  64 
27.  35404  PhD Jernej Pavšič  Pharmacy  Junior researcher  2012 - 2014  31 
28.  29617  PhD Marko Petek  Biotechnology  Researcher  2009 - 2014  160 
29.  24505  PhD Manca Pirc  Biotechnology  Junior researcher  2009 - 2010  201 
30.  18467  PhD Maruša Pompe Novak  Biotechnology  Researcher  2009 - 2014  287 
31.  30090  PhD Nina Prezelj  Biology  Junior researcher  2009 - 2014  58 
32.  34504  PhD Nejc Rački  Biotechnology  Junior researcher  2011 - 2014  56 
33.  34502  PhD Živa Ramšak  Biology  Junior researcher  2011 - 2014  116 
34.  05229  PhD Maja Ravnikar  Biotechnology  Head  2009 - 2014  1,352 
35.  27542  PhD Tomaž Rijavec  Microbiology and immunology  Junior researcher  2009  242 
36.  27503  PhD Ana Rotter  Biotechnology  Researcher  2009 - 2014  319 
37.  33224  PhD Matevž Rupar  Biotechnology  Junior researcher  2010 - 2014  55 
38.  12278  PhD Maja Rupnik  Microbiology and immunology  Researcher  2009 - 2013  668 
39.  32092  PhD Tjaša Stare  Biochemistry and molecular biology  Junior researcher  2009 - 2014  69 
40.  33271  PhD Jure Škraban  Biotechnology  Junior researcher  2010 - 2012  56 
41.  32096  PhD Ida Šmid  Pharmacy  Junior researcher  2009 - 2014  19 
42.  09864  PhD Magda Tušek Žnidarič  Biology  Researcher  2010 - 2014  409 
43.  03765  PhD Jana Žel  Biotechnology  Researcher  2009 - 2014  614 
Organisations (2)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0105  National Institute of Biology  Ljubljana  5055784  13,309 
2.  2334  University of Maribor, Faculty of Medicine  Maribor  5089638048  16,251 
Significance for science
The main strength of the research program which moves the borders of knowledge was in making connections between diverse disciplines (microbiology and plant biology, molecular biology, bioinformatics, biostatistics, computer sciences) in order to solve biological questions. Special emphasis was given to the analysis of multitrofic challenges including metagenomics to better understand the complex network of interactions in the ecosystem. The novelty was also the complexity of research approaches and introduction of different spatial and temporal levels in which we combined a set of non-invasive techniques to monitor selected components of plant defense and standard omics techniques that were downscaled to allow for analysis of small tissue sections. In our study we focused on the genes, proteins and final metabolic products to feed the dynamical models. Some genes recognized to be involved in the process of pathogen infection and plant recovery might prove to be useful markers for early detection of the disease, markers for resistance and recovery, and possible targets for biological control of the disease. Through the development of new strategies for the identification of new GMOs we have gained a new scientific knowledge and develop new tools with their potential use in other related fields. Methods allowing absolute quantification have opened a new era in more accurate and simpler preparation of reference materials. Metrological aspects of the research will provide a sound basis for reliable quantification and qualification of nucleic acids and cells. In particular, metrological approaches will be first implemented to harmonize international approaches of detection and identification of GMOs and human pathogens. Results of the program have been already published in the most prestigious scientific journals. They will be of great importance to develop new strategies for plant protection, food and water safety, as well as for developing new tools in molecular biology and molecular diagnostics.
Significance for the country
Taking into account the geographic position of Slovenia and current agro-economic trends, we investigated harmful plant pathogens that have been already present in Slovenia or we anticipated their occurrence in near future. The understanding of pathogen biology and mechanisms of disease development is a prerequisite for the development of appropriate strategies for their control and risk assessment for introduced technologies to the agronomical practice. We aimed to develop efficient and sustainable biotechnological and biological control methods and new strategies for food and water safety, without an extensive use of pesticides and keeping in mind conservation of great biodiversity in Slovenia. We are a National reference laboratory for determination of GMOs in food, feed and seeds accredited by the Slovenian accreditation for detection of genetically modified organisms and microorganisms – plant pathogens. We are also involved in development of standards for GMOs detection, both authorized and unauthorized, and microorganisms at CEN and ISO level. Our knowledge about genetic modification of plants has already supported implementation of Slovene and European legislation on food safety, plant and environment protection and GMOs. We have been authorized for measuring and counting molecules since 2009, when the metrology institute MIRS appointed our department as a holder of national measurement standard for the amount of substance in food of plant origin in the food safety area. Additionally, we have offered professional support and diagnosis for the Administration of the Republic of Slovenia for Food Safety, Veterinary and Plant Protection. For the Administration we have provided diagnostics for several quarantine microorganisms that cause diseases on stone fruit trees, grapevine and other plants and new emerging diseases. Up till now we have found for the first time more than 20 plant pathogens, most of them with quarantine status in Slovenia and EU, some of them were one of the first finding in Europe. Strong and ongoing collaborations with research groups at the national and worldwide level have been implemented in joint projects and publications and have resulted in access to the international know-how as well as to promotion of Slovenia in the international scientific community. Our involvement in the EU platforms for systems biology and bioinformatics (ISBE and ELIXIR) is an opportunity for Slovenia to have wider access to research as well as to computing infrastructure. Our research and expertise is of high relevance for industry. We have tightly cooperated with many companies working in agriculture, biotechnology and pharmacy. Our knowledge on systems biology and bioinformatics has qualified us to perform contract research with pharmaceutical company Lek d.d. Sandoz for many years. With a high-tech biotechnological company BiaSeparations we developed new biotechnological applications for concentration and purification of viruses, which have opened a whole new area in detection and elimination of water borne pathogens. Together with our spin-off company BioSistemika we have organized practical hands-on international workshops on molecular biology (qPCR) and developed software for automated molecular biology work. Together with company Omega we have built next generation sequencing platform. Our technological platforms for studies of human and plant pathogens are applicable in fields related to pharmacy, human and animal health, and environment. Six program researchers are actively involved in the undergraduate and graduate studies at the University of Ljubljana, University of Nova Gorica and International Postgraduate School Jožef Stefan and are mentors to many MSc and PhD students and thus the transfer of knowledge is guaranteed.
Audiovisual sources (1)
no. Title (with video link) Event Source
1. Biotehnologija in sistemska biologija rastlin (Slovene)    Research programme video presentation 
Most important scientific results Annual report 2009, 2010, 2011, 2012, 2013, final report, complete report on dLib.si
Most important socioeconomically and culturally relevant results Annual report 2009, 2010, 2011, 2012, 2013, final report, complete report on dLib.si
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